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pro vyhledávání: '"Kunhong Xiao"'
Autor:
Sharon L. Campbell, Stefan Knapp, Michelle Turski, Christopher M. Counter, Xiaojie Yao, Matt Crowe, Aaron Hobbs, Donita Brady, Kunhong Xiao, Dennis Thiele, Apirat Chaikuad
Publikováno v:
Molecular Cancer Research. 12:IA09-IA09
The BRAF serine/threonine kinase is mutated, typically at V600, to induce an active oncogenic state in a large fraction of melanoma, thyroid, hairy cell leukemia, and to a lesser extent, a wide spectrum of other cancers. BRAFV600E activates the kinas