Zobrazeno 1 - 2
of 2
pro vyhledávání: '"James R. Fuchs"'
Autor:
Jiayuh Lin, James R. Fuchs, Pui-Kai Li, Eric B. Schwartz, Jiagao Lü, Li Lin, Stephanie Deangelis, Elizabeth Foust, Dale G. Hoyt, Don M. Benson, Gregory B. Lesinski, Chenglong Li
Publikováno v:
Molecular Cancer, Vol 9, Iss 1, p 217 (2010)
Molecular Cancer
Molecular Cancer
Background Targeting Signal Transducer and Activator of Transcription 3 (STAT3) signaling is an attractive therapeutic approach for most types of human cancers with constitutively activated STAT3. A novel small molecular STAT3 inhibitor, FLLL32 was s
Autor:
Gregory B. Lesinski, Eric B. Schwartz, Dale G. Hoyt, Courtney E. Bakan, William E. Carson, James R. Fuchs, Dalia Abdelhamid, Jiayuh Lin, Jennifer Yui, Pui-Kai Li, Matthew A. Bill, Chenglong Li, Gregory S. Young, Don M. Benson, Stacey L. Fossey
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 9, Iss 1, p 165 (2010)
Molecular Cancer, Vol 9, Iss 1, p 165 (2010)
Background: We characterized the biologic effects of a novel small molecule STAT3 pathway inhibitor that is derived from the natural product curcumin. We hypothesized this lead compound would specifically inhibit the STAT3 signaling pathway to induce