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Autor:
Mohd W. Nasser, Helong Zhao, Yadwinder S. Deol, Amita Sneh, Mustafa M. Basree, Akaansha Ganju, Ramesh K. Ganju, Tasha Wilkie
Publikováno v:
Molecular Cancer
Introduction S100A7 (Psoriasin) is an inflammatory protein known to be upregulated in breast cancer. However, the role of S100A7 in breast cancer has been elusive, since both pro- and anti-proliferative roles have been reported in different types of
Autor:
Rose, Michael, Kloten, Vera, Weiskirchen, Ralf, Klaas, Oliver, Antonopoulos, Wiebke, Lin, Qiong, Wagner, Wolfgang, Veeck, Jürgen, Gremse, Felix, Steitz, Julia, Knüchel-Clarke, Ruth, Dahl, Edgar, Noetzel, Erik Alexander, Gola, Lukas, Ehling, Josef Ludger Anton, Heide, Timon, Meurer, Steffen K., Gaiko-Shcherbak, Aljona, Sechi, Antonio S., Huth, Sebastian
Publikováno v:
Molecular Cancer
Molecular cancer 16(1), 44 (2017). doi:10.1186/s12943-017-0610-2
Molecular cancer 16(1), 44 (2017). doi:10.1186/s12943-017-0610-2
Molecular cancer 16(1), 44 (2017). doi:10.1186/s12943-017-0610-2
Published by Biomed Central, London
Published by Biomed Central, London
Autor:
Lan Xiaopeng, Xiao Zhangwu, Jianwen Que, Qiong Hu, Jian Zhu, Qiaojia Huang, Zhang Rui, Gao Anding, Xie Fu'an, Haikun Wang, Kuancan Liu, Baoshun Lin, Weifeng Huang, Long Zhang
Publikováno v:
Molecular Cancer
Background High levels of SOX2 protein are correlated with increased dissemination of breast cancer. However, the underlying molecular mechanisms are not fully understood. Methods In this study we investigate the role of SOX2 in breast cancer metasta
Autor:
Sujoy Ghosh, Cui Rong Teo, Emmanuel Beillard, Wei Zhou, Patrick J. Casey, Suhail Ahmed Kabeer Rasheed, P. Mathijs Voorhoeve
Publikováno v:
Molecular Cancer
Background Gα13 (GNA13) is the α subunit of a heterotrimeric G protein that mediates signaling through specific G protein-coupled receptors (GPCRs). Our recent study showed that control of GNA13 expression by specific microRNAs (miRNAs or miRs) is
Publikováno v:
Molecular Cancer
Background Restin belongs to MAGE superfamily and is known as MAGE H1. Restin was firstly cloned from HL-60 cells treated with all-trans retinoic acid (ATRA). Previous studies showed a pro-apoptotic role of Restin in several cell lines. However, litt
Autor:
Amita Sneh, Ramesh K. Ganju, Yadwinder S. Deol, Tasha Wilkie, Mustafa M. Basree, Mohd W. Nasser, Akaansha Ganju, Helong Zhao
Publikováno v:
Molecular Cancer
S100A7 (Psoriasin) is an inflammatory protein known to be upregulated in breast cancer. However, the role of S100A7 in breast cancer has been elusive, since both pro- and anti-proliferative roles have been reported in different types of breast cancer
Publikováno v:
Molecular Cancer
Background Breast cancer stem cells (CSCs) are small sub-type of the whole cancer cells that drive tumor initiation, progression and metastasis. Recent studies have demonstrated a role for the aryl hydrocarbon receptor (AhR)/cytochrome P4501A1 pathwa
Autor:
Mark M. Schneider, Nichole Peterson, Sandip SenGupta, Jennifer M Roche, Rachel E. Rubino, Christopher J. Nicol, Anthony J. Apostoli, Michael Di Lena
Publikováno v:
Molecular Cancer
Background Among women worldwide, breast cancer is the most commonly diagnosed cancer, and the second leading cause of cancer-related deaths. Improved understanding of breast tumourigenesis may facilitate the development of more effective therapies.
Autor:
Sashko Damjanovski, Hon S. Leong, Jacob J. H. Pelling, Jessica A. Willson, Zoey Freedman, Ioana Stan, Karla C. Williams, Caitlin L. Evered, Mario A. Cepeda
Publikováno v:
Molecular Cancer
Paediatrics Publications
Paediatrics Publications
Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a multifunctional protease implicated in metastatic progression ostensibly due to its ability to degrade extracellular matrix (ECM) components and allow migration of cells through the b
Autor:
Hiroshi Yoshida, Yuko Tanabe, Kenji Tamura, Takashi Kohno, Mamoru Kato, Noboru Yamamoto, Satoru Iwasa, Atsushi Ochiai, Takashi Kubo, Hitoshi Ichikawa, Yasuhiro Fujiwara
Publikováno v:
Molecular Cancer
It is still controversial whether comprehensive genome screening of target molecules by next generation sequencing (NGS) is needed to increase clinical efficacy of investigational drugs or accelerate drug development, although several studies are bei