Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Adam Antczak"'
Publikováno v:
Molecular Biology Reports. 46:6593-6597
Two suppressor genes which often undergo epigenetic silencing during the early stages of lung carcinogenesis are those encoding retinoic acid receptor-β (RARβ) and Fhit protein (FHIT). RARβ expression is regulated by miRNA-34a and miRNA-141, and F
Autor:
Adam Antczak, Jacek Kordiak, Justyna Kiszałkiewicz, Katarzyna Góralska, Sławomir Jabłoński, Monika Migdalska-Sęk, Kamila Baran, Ewa Brzeziańska-Lasota
Publikováno v:
Molecular Biology Reports. 46:5389-5396
CC chemokine receptor type 7 (CCR7) and its ligands has been implicated in the occurrence and progression of NSCLC. Previous studies have revealed that the diagnostic value of CCR7/CCL19 axis in lung tumorigenesis remains controversial. The present s
Publikováno v:
Molecular Biology Reports
N363S and ER22/23EK polymorphisms observed within glucocorticoid receptor gene (NR3C1) may play an important role in the development of bronchial asthma. NR3C1 gene is associated with an altered sensitivity to GCs. The aim of the research project was
Autor:
Maciej Banasiak, Andrzej Witusik, Michał Panek, Janusz Szemraj, Paweł Górski, Adam Antczak, Tadeusz Pietras
Publikováno v:
Molecular Biology Reports. 39:2163-2167
Cyclooxygenase two (COX-2) is an important enzyme metabolizing arachidonic acid. In contrast to constitutive cyclooxygenase one (COX-1), COX-2 is induced by proinflammatory factors. Polymorphism -765 G/C in COX-2-encoding gene promoter is associated
Autor:
Daria Domańska, Paweł Górski, Ewa Nawrot, Dorota Pastuszak-Lewandoska, Ewa Brzeziańska, Jacek Kordiak, Karolina H. Czarnecka, Adam Antczak, Dorota Kaleta, Monika Migdalska-Sęk
Publikováno v:
Molecular Biology Reports
In lung cancer pathogenesis, genetic instability, i.e., loss of heterozygosity (LOH) and microsatellite instability (MSI) is a frequent molecular event, occurring at an early stage of cancerogenesis. The presence of LOH/MSI in non-small cell lung car