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pro vyhledávání: '"Zhiying Yang"'
Autor:
Fengxiao Xiong, Cheng Chen, Zhiying Yang, Junying Huang, Xiaojuan Chao, Shaogui Wang, Heqing Huang
Publikováno v:
Molecular and Cellular Endocrinology. 434:135-143
Diabetic nephropathy (DN) is the leading cause of end-stage renal failure and is characterized by excessive deposition of extracellular matrix (ECM) proteins such as fibronectin (FN), in the glomerular mesangium and tubulointerstitium. Betulinic acid
Autor:
Cheng Chen, Junying Huang, Fengxiao Xiong, Jie Hao, Peiqing Liu, Zhiying Yang, Kaipeng Huang, Heqing Huang
Publikováno v:
Molecular and cellular endocrinology. 427
We previously demonstrated that activation of sphingosine kinase 1 (SphK1)- sphingosine 1- phosphate (S1P) signaling pathway by high glucose (HG) plays a pivotal role in increasing the expression of fibronectin (FN), an important fibrotic component,