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Autor:
Laura Naldi, Alessandro Peri, Federica Baldanzi, G. Marroncini, Simone Polvani, Benedetta Fibbi, Cecilia Anceschi, Serena Martinelli, Mario Maggi
Publikováno v:
Molecular and cellular endocrinology. 537
Purpose Hyponatraemia is frequently observed in cancer patients and can be due to the syndrome of inappropriate anti-diuresis (SIAD), related to ectopic vasopressin secretion, particularly in small cell lung cancer (SCLC). Hyponatraemia is associated
Autor:
Yong Kyoo Shin, Ji Hoon Jeong, Joon Seok Bang, Do Hyeon Pyun, A. M. Abd El-Aty, Jin-Ho Song, Hyunjung Lee, Tae Jin Kim, Tae Woo Jung
Publikováno v:
Molecular and cellular endocrinology. 534
Capmatinib (CAP) has been used to treat metastatic non-small lung cancer (NSCL) and suppress inflammation. It causes hypoglycemia in NSCL patients. Therefore, it is expected that CAP improves inflammation-mediated insulin resistance due to its anti-i
Autor:
Yi-zhen Yang, Yu-Dong Liu, Xiao-Fei Zhang, Ying Li, Ying-Xue Chen, Zhe Wang, Xin Li, Jun Zhang, Xiao-min Wu, Shi-Ling Chen, Xing-Yu Zhou, Lin-zi Ma
Publikováno v:
Molecular and cellular endocrinology. 535
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in reproductive-aged women, and its pathogenesis is still under debate. Recent studies suggest crucial roles for microRNAs (miRNAs) in PCOS development. The let-7 family mi
Autor:
Luca Franco Castelnovo, Peter Thomas
Publikováno v:
Molecular and cellular endocrinology. 531
Membrane progesterone receptors (mPRs) were recently found to be present and active in Schwann cells, where they have a potentially pro-regenerative activity. In this study, we investigated the role of mPRs in human adipose stem cells (ASC) different
Publikováno v:
Molecular and cellular endocrinology. 537
Ataxin-3 (ATXN3) is a ubiquitous deubiquitinating enzyme that plays an essential role in the carcinogenesis of numerous tumors and stabilizes the expression of substrates by deubiquitination. However, the functional role of ATXN3 in anaplastic thyroi
Autor:
Pascal Boileau, Say Viengchareun, Laurent M. Sachs, Marc Lombès, Eric Pussard, Thi An Vu, Laetitia Martinerie, Mireille Castanet
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2021, 535, pp.111375. ⟨10.1016/j.mce.2021.111375⟩
Molecular and Cellular Endocrinology, 2021, 535, pp.111375. ⟨10.1016/j.mce.2021.111375⟩
Molecular and Cellular Endocrinology, Elsevier, 2021, 535, pp.111375. ⟨10.1016/j.mce.2021.111375⟩
Molecular and Cellular Endocrinology, 2021, 535, pp.111375. ⟨10.1016/j.mce.2021.111375⟩
International audience; Sodium and water homeostasis are drastically modified at birth, in mammals, by the transition from aquatic life to terrestrial life. Accumulating evidence during the past ten years underscores the central role for the mineralo
Autor:
Juilee Rege, William E. Rainey, Chia Jen Liu, Aaron M. Udager, Samuel W. Plaska, Zhaoping Qin, Jessica E Baker
Publikováno v:
Mol Cell Endocrinol
Adequate access to fresh or frozen normal adrenal tissue has been a primary limitation to the enhanced characterization of the adrenal zones via RNA sequencing (RNAseq). Herein, we describe the application of targeted RNAseq to formalin-fixed paraffi
Autor:
Trevor M. Penning
Publikováno v:
Mol Cell Endocrinol
Aldo-Keto-Reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase (HSD)/prostaglandin (PG) F(2α) synthase) is the only 17β-HSD that is not a short-chain dehydrogenase/reductase. By acting as a 17-ketosteroid reductase, AKR1C3 produces potent androg
Autor:
Jill M. Daniel, Kevin J. Pollard
Publikováno v:
Mol Cell Endocrinol
Non-canonical mechanisms of estrogen receptor activation may continue to support women’s cognitive health long after cessation of ovarian function. These mechanisms of estrogen receptor activation may include ligand-dependent actions via locally sy
Autor:
Thatchawan Thanasupawat, Sai Nivedita-Krishnan, Aleksandra Glogowska, Sabine Hombach-Klonisch, Brian C. Wilson, Thomas Klonisch
Publikováno v:
Molecular and Cellular Endocrinology. 487:85-93
A role for the hormone relaxin in cancer was described well before the receptor was identified. Relaxin predominantly increases the growth and invasive potential in cancers of different origins. However, relaxin was also shown to promote cell differe