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Publikováno v:
Molecular and cellular endocrinology. 534
The roles of signal transducer and activator of transcription 3 (STAT3) in inflammation, oxidative stress, and adipogenesis during Graves’ orbitopathy (GO) are incompletely understood. Here, STAT3 expression in orbital tissues (from individuals wit
Autor:
Jiashuo Li, Haiying Wang, Bin Xu, Xianchao Du, Wei Liu, Minghui Li, Bingchen Liu, Yanqi Sang, Xinxin Yang, Zhao-Fa Xu, Haibo Yang, Yanan Liu, Zhipeng Qi, Yu Deng
Publikováno v:
Molecular and Cellular Endocrinology. 542:111523
The GABAA receptor (GABAAR) plays important roles in the regulation of Mn-induced GnRH secretion in immature female rats. However, the underlying molecular mechanisms remain unknown. Here, we assessed whether FTO and its substrate m6A are correlated
Autor:
Ingibjörg Eir Einarsdottir, R.H. Springer-Miller, B. Th. Björnsson, D.A. Chenoweth, S. D. McCormick, A.L. Paskavitz, A.Y.H. Chang, Jason P. Breves, Amy M. Regish
Publikováno v:
Molecular and cellular endocrinology. 518
The growth hormone (Gh)/insulin-like growth-factor (Igf)/Igf binding protein (Igfbp) system regulates growth and osmoregulation in salmonid fishes, but how this system interacts with other endocrine systems is largely unknown. Given the well-document
Autor:
Edson Henrique Pereira de Arruda, Egberto Gaspar de Moura, Chaiane Aline da Rosa-Santos, Gleicielly Leite Vieira da Silva, Marise Auxiliadora de Barros Reis, Edson Moleta Colodel, Márcia Queiroz Latorraca, Vanessa Cristina Arantes, Patricia Cristina Lisboa, Everardo M. Carneiro, Amílcar Sabino Damazo
Publikováno v:
Molecular and cellular endocrinology. 518
We evaluated whether protein restriction during pregnancy alters the morphometry of pancreatic islets, the intra-islet glucagon-like peptide-1 (GLP-1) production, and the anti-apoptotic signalling pathway modulated by GLP-1. Control non-pregnant (CNP
Autor:
Michele Campaigne Larsen, Anbarasi Kothandapani, Colin R. Jefcoate, Joan S. Jorgensen, Jinwoo Lee
Publikováno v:
Molecular and Cellular Endocrinology. 531:111265
STARD1 stimulates cholesterol transfer to mitochondrial CYP11A1 for conversion to pregnenolone. A cholesterol-binding START domain is guided by an N-terminal domain in a cell selective manner. Fetal and adult Leydig cells (FLC, ALC) show distinct Sta
Publikováno v:
Molecular and Cellular Endocrinology. 442:81-89
We have previously reported that LHCGR expression in the ovary is regulated through a post-transcriptional mechanism involving an mRNA binding protein designated as LRBP, which is regulated, at least in part, by a non-coding RNA, miR-122. Our present
Publikováno v:
Molecular and cellular endocrinology. 500
High ambient temperature-related male reproduction disruptions are well illustrated across species, the effects on circadian oscillation in reproduction hormones and testicular steroidogenesis remain unclear. Here, we showed the changes in circadian
Autor:
Vinod Kumar, Amit Kumar Trivedi, Neelu Jain Gupta, Aakansha Sharma, Sayantan Sur, S. K. Tahajjul Taufique
Publikováno v:
Molecular and cellular endocrinology. 493
We investigated the temperature effects on hypothalamic transcription of genes involved in the induction of photoperiodic response in redheaded buntings. Birds were exposed at 22 and 38 °C to 13-h long photoperiods (LP), with controls at 22 °C on 8
Autor:
Zhe Bao Wu, Hao Tang, Wanqun Xie, Qun Li, Bohan Ren, Yongzhi Zheng, Zerui Wu, Zhipeng Su, Lin Cai, Yong Zhang, Yijun Cheng
Publikováno v:
Molecular and Cellular Endocrinology. 518:111033
Dopamine agonists (DAs), such as cabergoline and bromocriptine, are the first-line clinical treatment for prolactinomas. Our previous study demonstrated that long noncoding RNA H19 expression is frequently downregulated in human primary pituitary ade
Publikováno v:
Molecular and Cellular Endocrinology. 420:1-10
The ventrolateral division of the hypothalamic ventromedial nucleus (VMNvl) is a brain center for estrogen-dependent triggering of female sexual behavior upon progesterone receptor (PR) activation. We examined the agonistic and antagonistic actions o