Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Molecular and Cellular Biochemistry. 270:89-97
Tumor microenvironment, which is characterized by hypoxia, low-glucose concentrations, high-lactate concentrations, low-extracellular pH, can alter the therapeutic response in tumors. In this study, we investigated whether hypoxia affects TRAIL-induc
Autor:
Yong J. Lee, Peter M. Corry
Publikováno v:
Molecular and Cellular Biochemistry. 202:1-8
Although the synthesis of angiogenic factors in hypoxic regions of solid tumors is recognized as one of the critical steps in tumor growth and metastasis, the signal transduction pathway involved in hypoxic induction of basic fibroblast growth factor
Autor:
Christine M. Berns, Peter M. Corry, Sandra Galoforo, Roman Klemenz, Robert V. Blackburn, Yong J. Lee
Publikováno v:
Molecular and Cellular Biochemistry. 170:31-42
We have previously shown that murine L929 cells do not express the small heat shock protein αB-crystallin upon exposure to thermal stress (Mol Cell Biochem 155: 51–60, 1996). In these studies, we demonstrate that L929 cells also fail to express α
Autor:
Kun-Liang Guan, Sandra Galoforo, Christine M. Berns, Alvaro Martinez, Peter M. Corry, Yong J. Lee, Xiao-yu Wu, Anjali K. Gupta
Publikováno v:
Molecular and Cellular Biochemistry. 170:23-30
We have investigated the effect of glucose deprivation treatment on the activation of mitogen activated protein kinases (MAPKs) in the drug-sensitive human breast carcinoma cells (MCF-7) and its drug resistant variant (MCF-7/ADR) cells. Western blots
Autor:
Peter M. Corry, Yong J. Lee, Sandra Galoforo, Robert V. Blackburn, Joong M. Cho, Christine M. Berns, Mark E. Ireland
Publikováno v:
Molecular and Cellular Biochemistry. 155:51-60
We investigated the role of alpha B-crystallin expression in the development of thermotolerance in murine L929 cells. An initial heat-shock of 10 min at 45 degrees C induced thermotolerance in these cells to a heat challenge at 45 degrees C administe
Publikováno v:
Molecular and Cellular Biochemistry. 144:27-34
It was reported that chemical stresses such as arsenite, cadmium or salicylate fail to induce synthesis of the inducible form of HSP70 (HSP70i). We report here that exposure of cells to higher doses of these chemical treatments induced significant sy
Publikováno v:
Molecular and Cellular Biochemistry. 155
We investigated the effect of hypoglycemic treatment on the activation of the AP-1 transcription factors and the regulation of basic fibroblast growth factor (bFGF) gene expression in multidrug resistant human breast carcinoma MCF-7/ADR cells. Northe
Publikováno v:
Molecular and cellular biochemistry. 137(2)
Previous studies have shown that a combination of low pH and quercetin (QCT) treatment following heat shock markedly suppresses and delays the expression of heat shock protein genes, particularly the HSP70 gene (Lee et al., Biochem. Biophys. Res. Com
Autor:
Geza Erdos, Peter M. Corry, Yong J. Lee, Stephen W. Carper, Lindali Curetty, Joong M. Cho, Jannifer S. Stromberg, Zi-Zheng Hou
Publikováno v:
Molecular and cellular biochemistry. 137(2)
We have previously reported the lack of HSP28 gene expression during acute and chronic thermotolerance development in L929 cells (J Cell Physiol 152: 118-125, 1992; Cancer Res 52: 5787, 1992). In contrast to HSP28, an extremely high level of inducibl