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Publikováno v:
Molecular and Cellular Biochemistry. 476:3951-3962
MicroRNA (miR)-17-5p has been investigated in many diseases as a regulator of disease progression and is highly expressed in acute myeloid leukemia (AML). However, potential mechanisms underlying the function of miR-17-5p in AML need more elucidation
Autor:
Huixuan Zeng, Hongjiao Liu, Cairong Zhu, Xiaoping Wu, Qiuling Liu, Yishan Huang, Tianzhu Long
Publikováno v:
Molecular and Cellular Biochemistry. 476:3635-3646
Metastasis is the main cause of poor prognosis in the advanced prostate cancer in clinic. Accumulating evidences have proposed that cell motility greatly contributes to the multiple steps of the metastatic process. MicroRNA-145 (miR-145) has been fou
Publikováno v:
Molecular and Cellular Biochemistry. 476:3551-3561
Vascular calcification is one of the most common effects of macrovascular complications in patients in aging with chronic kidney disease and diabetes. Previous studies showed that HOTAIR attenuated vascular calcification via the Wnt/β-catenin-signal
Publikováno v:
Molecular and Cellular Biochemistry. 476:2869-2876
This was an observational cross-sectional study which was done to assess the expression profile of STATs and SOCS genes in cystic fibrosis. The mRNA was isolated from peripheral blood mononuclear cells of CF patients in exacerbation, colonization and
Autor:
Tamara Nikolic Turnic, Vladimir Jakovljevic, Kristina Radoman, Zoran Citakovic, Dalibor Dragisic, Miroslav Mitrovic, Sergey Bolevich, Boris Djindjic, Danijela Tasic, Nebojša Tasić, Vladimir Zivkovic, Zorana Kovacevic
Publikováno v:
Molecular and Cellular Biochemistry. 476:2663-2673
The aim of the study was to examine the effect of 4-week supplementation of Alixir 400 PROTECT® (Standardized Aronia L. Melanocarpa Extract Extract-SAE) on clinical and biochemical parameters in patients with confirmed metabolic syndrome (MetS). Thi
Autor:
Mohammad Reza Abbaszadegan, Mehran Gholamin, Atena Mansouri, Maryam Lotfi Gharaie, Mohammad Mahdi Forghanifard, Reihaneh Alsadat Mahmoudian, Ali Alasti
Publikováno v:
Molecular and Cellular Biochemistry. 476:2465-2478
Matrix metalloproteinases (MMPs) play key roles in epithelial-mesenchymal transition (EMT) for the development of cancer cell invasion and metastasis. MMP-13 is an extracellular matrix (ECM)-degrading enzyme that plays crucial roles in angiogenesis,
Publikováno v:
Molecular and Cellular Biochemistry
The expression of macrophage inhibitory factor-1 (MIC-1) increases in patients with chronic hepatitis C (CHC), but whether MIC-1 level and its polymorphism affect the antiviral efficacy of CHC has not yet been reported. The present study aimed to inv
Publikováno v:
Molecular and Cellular Biochemistry. 476:2099-2109
NADPH oxidase (NOX) is a main producers of reactive oxygen species (ROS) that may contribute to the early pathogenesis of diabetic retinopathy (DR). ROS has harmful effects on endogenous neuro-survival factors brain-derived neurotrophic factor (BDNF)
Publikováno v:
Molecular and Cellular Biochemistry. 476:1871-1879
The aim of this study was to determine the expression of long-chain non-coding RNA (lncRNA) colon cancer-associated transcript 2 (CCAT2) in children with neuroblastoma and its effect on cancer cell growth. A polymerase chain reaction assay was carrie
Publikováno v:
Molecular and Cellular Biochemistry. 476:1651-1661
JS-K as an exogenous NO donor could release NO after activation by glutathione S-transferases (GSTs). The present study explores the effects of JS-K on MAPK pathway in HepG2 and Bel-7402 cells. JS-K significantly prompted apoptosis and SB203580 (a p3