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Publikováno v:
Metabolites, Vol 11, Iss 495, p 495 (2021)
Metabolites
Metabolites
Venous thromboembolism (VTE) is a condition comprising deep venous thrombosis (DVT) and pulmonary embolism (PE). The prevalence of this disease is constantly increasing and it is also a chief reason for morbidity. Therefore, the primary prevention of
Autor:
Dae Young Lee, Dahye Yoon, Hyoung Geun Kim, Bo Ram Choi, Tae Hoo Yi, Seon Min Oh, Young-Seob Lee, Kwan Woo Kim, Yung Choon Yoo
Publikováno v:
Metabolites, Vol 11, Iss 505, p 505 (2021)
Metabolites
Volume 11
Issue 8
Metabolites
Volume 11
Issue 8
The prevalence of obesity is rapidly increasing and is recognized as a serious health problem. To investigate metabolic changes in an obese model after administration of Acanthopanax sessiliflorus, mice were divided into four groups: normal diet, hig
Publikováno v:
Metabolites, Vol 11, Iss 379, p 379 (2021)
Metabolites
Volume 11
Issue 6
Metabolites
Volume 11
Issue 6
The effects of intravenous gefitinib (10 mg/kg), an anilinoquinazoline thymidylate kinase inhibitor (TKI), selective for the epidermal growth factor receptor (EGFR), on the urinary metabotypes of mice were studied. We hypothesized that, in response t
Publikováno v:
Metabolites, Vol 11, Iss 32, p 32 (2021)
Metabolites
Metabolites
Altered lipid metabolism has been associated with the progression of various cancers, and aberrant expression of enzymes involved in the lipid metabolism has been detected in different stages of cancer. Breast cancer (BC) is one of the cancer types k
Publikováno v:
Metabolites, Vol 11, Iss 51, p 51 (2021)
Metabolites
Metabolites
Biomarker discovery and implementation are at the forefront of the precision medicine movement. Modern advances in the field of metabolomics afford the opportunity to readily identify new metabolite biomarkers across a wide array of disciplines. Many
Autor:
Giuseppe Montalto, Giuseppa Castellino, Ali A. Rizvi, Carlo Castruccio Castracani, Angelo Maria Patti, Manfredi Rizzo, Dragana Nikolic, Rosaria Vincenza Giglio, Roberta Chianetta, Giovanni Li Volti, Antonio Magán-Fernández, Yajnavalka Banerjee, Anca Pantea Stoian, Giorgio Sesti
Publikováno v:
Metabolites, Vol 10, Iss 391, p 391 (2020)
Metabolites
Volume 10
Issue 10
Metabolites
Volume 10
Issue 10
Liraglutide has shown favourable effects on several cardiometabolic risk factors, beyond glucose control. MicroRNAs (miRNAs) regulate gene expression, resulting in post-transcriptional modifications of cell response and function. Specific miRNAs, inc
Autor:
Nuria de Pedro, Jesús Martín, José R. Tormo, Gloria Crespo, Víctor González-Menéndez, Clara Toro, Olga Genilloud
Publikováno v:
Metabolites, Vol 9, Iss 10, p 197 (2019)
Metabolites
Volume 9
Issue 10
Metabolites
Volume 9
Issue 10
Fungi are one of the most prolific sources of microbial secondary metabolites. The production of new metabolites can be achieved using multiple fermentation conditions and by adding small-molecule effectors, including epigenetic modifiers. In the fra
Autor:
Tzu-Yi Wang, Jung-San Chang, I-Jeng Yeh, Chiung-Yu Peng, Fen-Wei Chen, Pei‑Lin Wu, Tzeng-Jih Lin, Yueh-Lun Shih, Yao-Hua Liu, Meng-Chi Yen, Jhong-Ching Lin
Publikováno v:
Metabolites, Vol 9, Iss 9, p 172 (2019)
Metabolites
Volume 9
Issue 9
Metabolites
Volume 9
Issue 9
Chromium (Cr) is a well-known heavy metal that can cause renal damage. The production of reactive oxygen species (ROS) due to chromium-induced toxicity induces cell dysfunction, apoptosis, and death. N-acetylcysteine (NAC) is an antioxidant used as a
Publikováno v:
Metabolites, Vol 11, Iss 480, p 480 (2021)
Metabolites
Volume 11
Issue 8
Metabolites
Volume 11
Issue 8
The biguanide drug metformin has been widely used for the treatment of type 2 diabetes, and there is evidence supporting the anticancer effect of metformin despite some controversy. Here, we report the growth inhibitory activity of metformin in the b
Autor:
Yvette L Schooneveldt, Anna C. Calkin, Aaron W Jurrjens, Michael F Keating, Sudip Paul, Natalie A. Mellett, Peter J. Meikle, Corey Giles
Publikováno v:
Metabolites
Volume 11
Issue 6
Metabolites, Vol 11, Iss 340, p 340 (2021)
Volume 11
Issue 6
Metabolites, Vol 11, Iss 340, p 340 (2021)
Statins are the first-line lipid-lowering therapy for reducing cardiovascular disease (CVD) risk. A plasma lipid ratio of two phospholipids, PI(36:2) and PC(18:0_20:4), was previously identified to explain 58% of the relative CVD risk reduction assoc