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Autor:
Anish G. R. Potty, R. Justin Mistovich, Craig Cady, Nicola Maffulli, Hugo C. Rodriguez, Anne-Marie Fauser, Ashim Gupta
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9364, p 9364 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9364, p 9364 (2020)
Stem cells for regenerative medicine purposes offer therapeutic benefits, but disadvantages are still ill defined. The benefit of stem cells may be attributed to their secretion of growth factors (GFs), cytokines (CKs), and extracellular vesicles (EV
Publikováno v:
Medicine and Science in Sports and Exercise, Vol. 49, p. 1552-1561 (2017)
This study aimed to determine whether fission and mitophagy are activated by acute endurance exercise in human skeletal muscle and to investigate if this activation is dependent upon the nutritional state. Trained athletes (n = 7) cycled for 2 h at 7
Publikováno v:
Medicine & Science in Sports & Exercise. 43:1441-1450
Purpose: The role of AMP-activated protein kinase a2 (AMPKa2) in regulating MEF2A nucleus translocation, nuclear histone deacetylase 5 (HDAC5) association with MEF2, HDAC5 nuclear export, MEF2A binding to the Glut4 promoter, and GLUT4 expression was
Autor:
Rachel K. Evans, Ran Yanovich, Naama Constantini, Eran Israeli, Drorit Merkel, Daniel S. Moran, Danit R. Shahar
Publikováno v:
Medicine & Science in Sports & Exercise. 40:S685-S690
The impact of iron deficiency is considerable when enhanced physical fitness is required. Female military recruits represent a unique population faced with intense physical and cognitive demands. Purpose: To examine the prevalence of iron deficiency
Autor:
Joseph W. Starnes, Ryan P. Taylor
Publikováno v:
Medicine & Science in Sports & Exercise. 39:1537-1543
It is now well established that exercise can result in cardioprotection against ischemia-reperfusion (I-R) injury; however, the adaptations within the heart that provide the protection are still in doubt. The cytoprotective proteins receiving the mos
Autor:
Sue C. Bodine
Publikováno v:
Medicine & Science in Sports & Exercise. 38:1950-1957
Skeletal muscle size is dynamic and responsive to extracellular signals such as mechanical load, neural activity, hormones, growth factors, and cytokines. The signaling pathways responsible for regulating cell size in adult skeletal muscle under grow
Autor:
Scot R. Kimball
Publikováno v:
Medicine & Science in Sports & Exercise. 38:1958-1964
The AMP-activated protein kinase (AMPK) has been referred to as an "energy sensor" because it binds to and is regulated by both AMP and ATP. The binding of AMP to AMPK allows it to be phosphorylated by upstream kinases, resulting in its activation. I
Autor:
Keith Baar
Publikováno v:
Medicine & Science in Sports & Exercise. 38:1939-1944
The classic work of Hickson demonstrated that training for both strength and endurance at the same time results in less adaptation compared with training for either one alone: this has been described as the concurrent training effect. Generally, resi
Autor:
Bruno Grassi
Publikováno v:
Medicine & Science in Sports & Exercise. 37:1567-1573
In "normal" conditions (e.g., normoxia, absence of pathological conditions) convective and diffusive O(2) delivery to skeletal muscle fibers do not seem to represent important determinants for the kinetics of adjustment of oxidative phosphorylation f
Autor:
Mary L. Ellsworth
Publikováno v:
Medicine & Science in Sports & Exercise. 36:35-41
Blood flow to skeletal muscle is a complex process designed to provide adequate, yet not excessive, amounts of oxygen to meet the ever-changing metabolic needs of the tissue. To accomplish this goal, a mechanism must exist that couples the oxygen nee