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Publikováno v:
Medicine
This study assessed the association of sirtuin type 1 (SIRT1) and survivin expression with the clinicopathological features and survival of esophageal squamous cell carcinoma (ESCC) patients after concurrent chemoradiotherapy. SIRT1 and survivin prot
Publikováno v:
Medicine
Although proliferating cell nuclear antigen (PCNA) plays an important role in tumor proliferation and its expression level is closely related to the biological activity of tumor cells, PCNA expression in non-small cell lung cancer (NSCLC) has been se
Autor:
Hongjun Zhu, Qing Zhang, Jian Liu, Yifei Liu, Jianguo Zhang, Hui Sun, Jia Feng, Tingting Bian, Xiaoli Li
Publikováno v:
Medicine
Targeting protein for Xenopus kinesin-like protein 2 (TPX2) has been identified as an oncogene in multiple cancers. However, the associations among TPX2 expression, prognosis, and tumor immunity in hepatic cell cancer (HCC) have not been explored. We
Autor:
Suhong Xie, Bing Xiu, Weizhe Qiu, Suxia Zhang, Xianghua Yi, Xia Fang, Long Zhang, Xuyou Zhu, Aibin Liang, Xue Chen, Yu Zeng, Yunjin Wu, Zhi-Zhang Yang
Publikováno v:
Medicine
Supplemental Digital Content is available in the text
Latest study showed that a novel translocation between programmed cell death ligand 1 (PD-L1) (cluster of differentiation 274) and TP63 (tumor protein 63) can be found in diffuse large B-cell
Latest study showed that a novel translocation between programmed cell death ligand 1 (PD-L1) (cluster of differentiation 274) and TP63 (tumor protein 63) can be found in diffuse large B-cell
Hypermethylation and Expression Silencing of PDCD4 Gene in Hepatocellular Carcinoma: A Consort Study
Publikováno v:
Medicine
Programmed cell death 4 (PDCD4) is a novel tumor suppressor, which is involved in the initiation and progression of cancers. However, the role of PDCD4 in hepatocellular carcinoma (HCC) has not been reported. The aim of this study was to investigate
Autor:
Jiansheng Wang, Yan Yan, Li Wang, Xiaoyi Duan, Jizhao Wang, Ya Yang, Jia Zhang, Xu Liu, Min Li
Publikováno v:
Medicine
Tumor-associated macrophages (TAMs) are associated with poor prognosis in numerous human cancers and play important roles in tumor progression. Epithelial-mesenchymal transition (EMT) contributes to invasion and metastasis in cancer. However, the ass
Autor:
Zekiye Altun, Nezih Özdemir, Atila Akkoclu, Safiye Aktaş, Ahmet Önen, Aydn Şanl, Ayse Banu Demir, Hasan Ersöz, Ismail Agababaoglu
Publikováno v:
Medicine
Background: Lung cancer is responsible of 12.4% and 17.6% of all newly diagnosed cancer cases and mortality due to cancer, respectively, and 5-year survival rate despite all improved treatment options is 15%. This survival rate reaches 66% in the Sta
Autor:
Eugenio Maiorano, Matteo Ferro, Pasquale Ditonno, Sabino De Placido, Silvano Palazzo, Simona Cagiano, Pantaleo Bufo, Francesca Sanguedolce, Margherita Gigante, Giuseppe Di Lorenzo, Vanessa Galleggiante, Giuseppe Lucarelli, Michele Battaglia, Loreto Gesualdo, Domenico Ribatti, Carlo Bettocchi, Carlo Buonerba, Elena Ranieri, Ottavio De Cobelli, Monica Rutigliano, Andrea Giglio
Publikováno v:
Medicine
Glucose-6-phosphate isomerase (GPI), also known as phosphoglucose isomerase, was initially identified as the second glycolytic enzyme that catalyzes the interconversion of glucose-6-phosphate to fructose-6-phosphate. Later studies demonstrated that G