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Autor:
Louis-Marie Terrier, Alexandre Carpentier, C.-A. Valéry, Philippe Cornu, Marc Lévêque, Jean-Jacques Mazeron, Aymeric Amelot
Publikováno v:
Medical oncology (Northwood, London, England). 34(11)
Little is known about the natural history of cancer and its evolution to metastasis. Paget was the first to postulate the important role played by microenvironment in metastasis progression. Since, the concept of his “seed and soil” theory has be
Autor:
Matteo Landriscina, Ludovica Borgia, Luciana Possidente, Giuseppe Patitucci, Giulia Vita, Vittoria Lalinga
Publikováno v:
Medical oncology (Northwood, London, England). 34(5)
Lung adenocarcinomas are characterized by a variety of genetic and epigenetic changes that lead to activation of specific signaling pathways. This allowed the classification of lung adenocarcinomas according to genetic alterations and the clinical de
Autor:
Maria Bellut, Gerd Wegener, Markus A. Kuczyk, Andres Jan Schrader, Jan U. Becker, Hendrik Eggers, Hans Kreipe, Anika Großhennig, Viktor Grünwald, Mahmoud Abbas, Sandra Steffens, Philipp Ivanyi
Publikováno v:
Medical oncology (Northwood, London, England). 33(6)
Clinical trials targeting programmed death 1 (PD-1) and its ligand PD-L1 (PD-L1) for metastatic renal cell cancer (RCC) are ongoing. The aim of this study is to validate their roles as prognostic markers in non-clear cell (non-cc) RCC. Sixty-four non
Autor:
Kwok Wah Chan, John M. Luk, Gopesh Srivastava, Yvonne Chung, Nikki P. Lee, Johnny Cheuk On Tang, Sai Wah Tsao, Simon Law, Kenneth K. Y. Lai, Marco K. C. Hui, Leo C. M. Cheung
Publikováno v:
Medical Oncology (Northwood, London, England)
To examine the correlation of survivin (both total and nuclear survivin) with clinicopathological parameters of esophageal squamous cell carcinoma (ESCC) patients. Tumors and non-tumor tissues near the proximal resection margins were resected from ES
Autor:
Georgios Alexiadis, Maria Lambropoulou, Athanasia Kotini, Alexandra K. Tsaroucha, Christina Nikolaidou, Theodora-Eleftheria Deftereou, Anastasia Kiziridou, Constantinos Anagnostopoulos, Sryridon Kynigopoulos, Nikolaos Papadopoulos, Ekaterini Chatzaki, Anargyros Patsias
Publikováno v:
Medical oncology (Northwood, London, England). 33(1)
Endometrial cancer is the sixth most common cancer in women. Galectin-3 (GAL-3) and CRIP-1 are multifunctional proteins which seem to be involved in many neoplasias. This study aims to point out correlations between clinicopathological findings and e
Publikováno v:
Medical oncology (Northwood, London, England). 31(12)
MET has been suggested to have an intimate relationship with small cell lung cancer (SCLC) and might be a promising therapeutic target. To date, relatively limited reports have been explored on MET mutational status in SCLC patients. To investigate t
Publikováno v:
Medical oncology (Northwood, London, England). 31(10)
MiR-106b~25 has been researched in several cancers. The aim of this study was to test miR-106b~25 expressions in 40 operative specimens and 20 pre-operative plasma samples of GC patients and explore the correlations between these miRNAs and some rela
Publikováno v:
Medical oncology (Northwood, London, England). 31(6)
The aim of this study was to investigate the associations of matrix metalloprotease-1 (MMP-1) and its receptor protease-activated receptor-1 (PAR-1) coexpression with the clinicopathological characteristics and prognosis of patients with prostate can
Autor:
Jia-Hong Chen, Zhuo-yuan Lin, Xiao-hui Ling, Zhao-Dong Han, Yan-Ru Chen, Xin Fu, Hui-chan He, Yu-Xiang Liang, Chao Cai, Ya-Qiang Huang, Qi-shan Dai, Xue-cheng Bi, Wei-de Zhong, Funeng Jiang
Publikováno v:
Medical oncology (Northwood, London, England). 31(1)
The aim of this study was to investigate the associations of myosin light chain (MYL9) downregulation with tumor progression and prognosis in patients with prostate cancer (PCa). MYL9 protein expression in human PCa and non-cancerous prostate tissues
Publikováno v:
Medical oncology (Northwood, London, England). 31(1)
The purpose of this study was to evaluate the association between epidermal growth factor receptor (EGFR) mutations and prognosis in patients with completely resected lung adenocarcinoma. A total of 131 patients were included in this study. EGFR muta