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Publikováno v:
Medical Oncology. 35
Inflammatory myofibroblastic tumor (IMT) is a mesenchymal neoplasm that may arise in soft tissues of nearly every organ. Although IMTs are the most common lung tumors in pediatric populations, these tumors are extremely rare in adults, constituting l
Autor:
Keiko Mamiya, Kazuhiro Oguchi, Tomonobu Koizumi, Kazunari Tateishi, Takashi Kobayashi, Nodoka Sekiguchi, Daisuke Gomi, Akane Katou, Toshirou Fukushima
Publikováno v:
Medical Oncology. 34
Recent advances in positron emission tomography with fluorine-18-fluorodeoxyglucose (FDG-PET) have facilitated not only the diagnosis and staging of lung cancer, but also the prediction of treatment outcome. The present study was designed to assess t
Publikováno v:
Medical Oncology. 34
Genes related to key cellular pathways are frequently altered in B cell ALL and are associated with poor survival especially in high-risk (HR) subgroups. We examined gene copy number abnormalities (CNA) in 101 Indian HR B cell ALL patients and their
Autor:
Wilko Weichert, Franziska Erlmeier, Michael Autenrieth, Arndt Hartmann, Andres J. Schrader, Max Wiedemann, Sandra Steffens, Philipp Ivanyi
Publikováno v:
Medical Oncology. 34
In the context of cancer immunotherapy, PD-1 as well as PD-L1 has been widely studied in renal cell carcinoma (RCC). PD-1 and PD-L1 play a significant role as prognostic markers in clear cell renal cell carcinoma. In contrast, little is known about P
Autor:
Mario Cezar Saffi Junior, Humberto Dellê, Cleber Pinto Camacho, Rodrigo Barbosa de Oliveira Brito, Ivone da Silva Duarte, Sergio Makabe, Giovana Garcia Prado
Publikováno v:
Medical Oncology. 33
Cervical cancer (CC) is one of the most common cancers among women worldwide. The relation of the human papillomavirus (HPV) with CC and its precursor lesions was first suspected for over 40 years. The indoleamine 2,3 dioxygenase (IDO) is an immune m
Autor:
Yoshihito Uchino, Yoshikazu Iizuka, Daisuke Kurita, Masaru Nakagawa, Katsuhiro Miura, Noriyoshi Iriyama, Yoshihiro Hatta, Masami Takei, Hiromichi Takahashi, Yujin Kobayashi, Masashi Sakagami, Hitomi Sakagami, Shimon Ohtake
Publikováno v:
Medical Oncology. 33
In this study, the impact of plasma cell maturity on the prognoses of multiple myeloma (MM) patients in the era of novel agents was investigated. Myeloma cell maturity was classified via immunophenotyping: myeloma cells showing mature plasma cell 1 (
Autor:
Justyna Kiszałkiewicz, Monika Migdalska-Sęk, Karolina H. Czarnecka, Daria Domańska-Senderowska, Dorota Pastuszak-Lewandoska, Ewa Nawrot, Ewa Brzeziańska-Lasota, Agata Karowicz-Bilińska
Publikováno v:
Medical Oncology. 33
In the present study, we analyzed (1) the type of HPV infection and (2) the frequency of loss of heterozygosity and microsatellite imbalance (LOH/MSI) in normal cytology and cervical intraepithelial neoplasia (CIN1-3). The cytological material includ
Publikováno v:
Medical Oncology. 33
Liquid biopsies such as circulating tumor DNA in plasma and disseminated tumor cells in the bone marrow are currently available. However, it is unclear which types of samples are appropriate for detecting tumor DNA in these biopsies. Here, we collect
Publikováno v:
Medical Oncology. 33
The purpose of this study is to explore the role of hypoxia on the invasion and metastasis of laryngeal carcinoma. The invasion and migration ability of laryngeal cancer SCC10A cell was detected by transwell assay. Western blot was applied to analyze
Autor:
Jingyu Zhang, Zhenwei Zhao, Fuqiang Feng, Yongsheng Zhang, Liang Wang, Huai-zhou Qin, Guodong Gao, Ji Peigang, Gang Li, Lihong Li, Yanyang Tu
Publikováno v:
Medical Oncology. 29:3491-3497
Recent studies have demonstrated that the chemokine CCL20 and its receptor CCR6 may be involved in tumorigenesis, tumor progression and metastatic spread of various human malignancies. The aim of this study was to investigate the clinicopathological