Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thirumalaisamy P. Velavan"'
Autor:
Moses Ikegbunam, Johnson A. Ojo, Kossiwa Kokou, Ugonna Morikwe, Chukwuemeka Nworu, Chibuzo Uba, Charles Esimone, Thirumalaisamy P. Velavan, Olusola Ojurongbe
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-6 (2021)
Abstract Background The occurrence of artemisinin resistance (ART)-associated polymorphism of Plasmodium falciparum K13-propeller (pfk13) gene before and after the introduction of artemisinin-based combination therapy (ACT) in two regions of Nigeria
Externí odkaz:
https://doaj.org/article/8a7192ce401c432e9b03a3673e625fba
Autor:
Bui Van Long, Genevieve Allen, Melanie Brauny, Le Thi Kieu Linh, Srinivas Reddy Pallerla, Tran Thi Thu Huyen, Hoang Van Tong, Nguyen Linh Toan, Do Quyet, Ho Anh Son, Thirumalaisamy P. Velavan
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-7 (2020)
Abstract Background While the World Health Organization (WHO) Southeast Asia region has the second highest incidence of malaria worldwide, malaria in Vietnam is focal to few provinces, where delayed parasite clearance to anti-malarial drugs is docume
Externí odkaz:
https://doaj.org/article/6b9986b50efa4a13a95f8e8470695a9c
Autor:
Louis Regis Dossou-Yovo, Francine Ntoumi, Felix Koukouikila-Koussounda, Jeannhey Christevy Vouvoungui, Ayodele Adedoja, David Nderu, Thirumalaisamy P. Velavan, Arsène Lenga
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-6 (2020)
Abstract Background Malaria in pregnancy is associated with considerable morbidity and mortality. Regular surveillance of artemisinin-based combination therapy tolerance, or molecular makers of resistance, is vital for effective malaria treatment, co
Externí odkaz:
https://doaj.org/article/a4ac3c2a27fb40daa4766a8f8ab04d66
Autor:
Bayode R. Adegbite, Jean R. Edoa, Yabo J. Honkpehedji, Frejus J. Zinsou, Jean C. Dejon-Agobe, Mirabeau Mbong-Ngwese, Fabrice Lotola-Mougueni, Erik Koehne, Albert Lalremruata, Andrea Kreidenweiss, The T. Nguyen, Jutta Kun, Selidji T. Agnandji, Bertrand Lell, Abdou R. Safiou, Fridia A. Obone Atome, Ghyslain Mombo-Ngoma, Michael Ramharter, Thirumalaisamy P. Velavan, Benjamin Mordmüller, Peter G. Kremsner, Ayola A. Adegnika
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background Malaria remains a major public health problem, affecting mainly low-and middle-income countries. The management of this parasitic disease is challenged by ever increasing drug resistance. This study, investigated the therapeutic e
Externí odkaz:
https://doaj.org/article/d16288ba442942598e824b48025d8d77
Autor:
Moses N. Ikegbunam, Charles N. Nkonganyi, Bolaji N. Thomas, Charles O. Esimone, Thirumalaisamy P. Velavan, Olusola Ojurongbe
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-7 (2019)
Abstract Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolate
Externí odkaz:
https://doaj.org/article/1b30c501f62749fe90b28ebd4cd6e91b
Autor:
Nerly Shirère Gampio Gueye, Simon Marie Peko, David Nderu, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Charles Kobawila, Thirumalaisamy P. Velavan, Francine Ntoumi
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-6 (2019)
Abstract Background Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria. However, this drug induces haemolytic anaemia among glucose-6-phosphate dehydrog
Externí odkaz:
https://doaj.org/article/ad02b3d064da4b9abc2391327a43824f
Autor:
Christian N. Nguetse, Ayola Akim Adegnika, Tsiri Agbenyega, Bernhards R. Ogutu, Sanjeev Krishna, Peter G. Kremsner, Thirumalaisamy P. Velavan
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Their frequency dist
Externí odkaz:
https://doaj.org/article/b9eb2a0e5e4c496985dec5a6d4f4045f
Autor:
Felix Koukouikila-Koussounda, Sankarganesh Jeyaraj, Christian N. Nguetse, Charles Nchotebah Nkonganyi, Kossiwa Clarisse Kokou, Mandingha K. Etoka-Beka, Francine Ntoumi, Thirumalaisamy P. Velavan
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-7 (2017)
Abstract Background Resistance to anti-malarial drugs hinders efforts on malaria elimination and eradication. Following the global spread of chloroquine-resistant parasites, the Republic of Congo adopted artemisinin-based combination therapy (ACT) in
Externí odkaz:
https://doaj.org/article/35b9427bb75349c4a5f957df450737ed
Autor:
Bolaji N. Thomas, Charles Nchotebah Nkonganyi, Olusola Ojurongbe, Moses Nkechukwu Ikegbunam, Thirumalaisamy P. Velavan, Charles O. Esimone
Publikováno v:
Malaria Journal
Malaria Journal, Vol 18, Iss 1, Pp 1-7 (2019)
Malaria Journal, Vol 18, Iss 1, Pp 1-7 (2019)
Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 yea
Autor:
Felix Koukouikila-Koussounda, Simon Marie Peko, Christevy Vouvoungui, David Nderu, Thirumalaisamy P. Velavan, Simon Charles Kobawila, Francine Ntoumi, Nerly Shirère Gampio Gueye
Publikováno v:
Malaria Journal
Malaria Journal, Vol 18, Iss 1, Pp 1-6 (2019)
Malaria Journal, Vol 18, Iss 1, Pp 1-6 (2019)
Background Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria. However, this drug induces haemolytic anaemia among glucose-6-phosphate dehydrogenase (G6