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Autor:
Chi Chiu Mok, Chak Sing Lau
Publikováno v:
Lupus. 9(4)
Objective: To study the profile of sex hormones in male patients with systemic lupus erythematosus (SLE). Method: Serum prolactin (PRL), testosterone (T), estradiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels were obt
Autor:
Dimitrios T. Boumpas, J Rairie, John C. Davis, D Sinicropi, Susan Manzi, D Averthelyi, James E. Balow, V G Hale, Iain B. McInnes, Cheryl Yarboro, Howard A. Austin, John H. Klippel
Publikováno v:
Lupus. 8(1)
Systemic lupus erythematosus (SLE) is characterized by the production of pathogenic autoantibodies to nucleoprotein antigens, including double-stranded DNA (dsDNA). The deposition of IgG dsDNA immune complexes in glomeruli is thought to be crucial fo
Autor:
Donato Alarcón-Segovia, Hector Melin-Aldana, Gilberto Vargas-Alarcón, Julio Granados, Felipe Andrade, Jorge Alcocer-Varela
Publikováno v:
Scopus-Elsevier
Alleles of the major histocompatibility complex (MHC) have been recognized as genetic factors for the development of SLE. The [HLA-B8; SC01; DR3] extended haplotype seems to be relevant in patients from white European descent, pertinent alleles, howe