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pro vyhledávání: ''
Autor:
Kaiyan Chen, Xiaoqing Yu, Zhiyu Huang, Yun Fan, Guoping Cheng, Yanjun Xu, Fanrong Zhang, Guanxia Zhu
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 142
The efficacy of immunotherapy in epidermal growth factor receptor (EGFR)-activating non-small cell lung cancer (NSCLC) is limited. However, a series of patients with uncommon EGFR alterations was reported to derive clinical benefit from PD-1 blockade
Autor:
Aya Miyagawa-Hayashino, Masayoshi Inoue, Yuta Sonobe, Takahiro Yamada, Tadaaki Yamada, Satoru Okada, Masahiro Iwasaku, Koichi Takayama, Yusuke Chihara, Eiichi Konishi, Tatsuya Imabayashi, Takayuki Shimamoto, Yoshiko Kaneko, Akihiro Yoshimura, Junji Uchino
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 137
Objective Small cell lung cancer (SCLC), which accounts for approximately 15% of all lung cancer cases, has high initial sensitivity to chemotherapy. However, clinical outcomes have not improved in the past two decades. Therefore, novel biomarkers ar
Autor:
Yataro Daigo, Hidetoshi Sumimoto, Jun Hanaoka, Koji Teramoto, Tomoyuki Igarashi, Mitsuaki Ishida, Yoko Kataoka
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 137
Objectives Cancer-associated fibroblasts (CAFs) are a dominant cell type in tumor stroma and support the generation of pro-tumorigenic microenvironment. CAFs have frequent opportunities to interact with immune cells infiltrating the tumor stroma, but
Autor:
Zhonghua Xu, Chang Chen, Yongbing Chen, Yongsheng Zhang, Junmiao Wen, Donglai Chen, Xiaofan Wang, Qifeng Ding
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 134
To further investigate the relationship between the cribriform component and spread through air spaces (STAS), and to unravel the potential pathological mechanism of poor prognoses in lung adenocarcinoma (LUAD) patients with a cribriform component.We
Autor:
Masahiro Tsuboi, Tomohiro Ichikawa, Keiju Aokage, Kenji Suzuki, Tomohiro Miyoshi, Genichiro Ishii, Hideki Makinoshima, Kenta Tane
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 136
The purpose of this study was to investigate whether fluorodeoxyglucose (FDG) accumulation is associated with the expression of microenvironmental factors in radiological pure-solid lung adenocarcinoma.We selected 50 cases involving patients with cli
Autor:
Tadashi Handa, Yasuhiko Koga, Kimihiro Shimizu, Tetsunari Oyama, Hiroaki Masubuchi, Kyoichi Kaira, Takehiko Yokobori, Koichi Yamaguchi, Reiko Sakurai, Kenichiro Hara, Norimitsu Kasahara, Takeshi Hisada, Takayuki Asao, Tetsuya Higuchi, Hiroaki Tsurumaki
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 134
Objectives Positron emission tomography (PET) using 2-deoxy-2-[18F] fluoro-D-glucose (18F-FDG) is a clinically useful modality for cancer evaluation. The mechanism of 18F-FDG uptake within cancer cells involves the glucose transporter 1 (GLUT1) and h
Autor:
Koushi Yokomura, Yuzo Suzuki, Haruhiko Sugimura, Hiroshi Ogawa, Yuji Iwashita, Naoki Inui, Kazutaka Mori, Tomoaki Kahyo, Katsuhiro Yoshimura, Kazuo Tsuchiya, Masayuki Tanahashi, Takafumi Suda, Hiroshi Niwa, Masato Karayama, Kazuhito Funai, Akikazu Kawase, Yusuke Inoue, Kazuya Shinmura
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 134
Objectives Most patients with non-small cell lung cancer (NSCLC) are diagnosed at advanced stages where small biopsy specimens obtained through endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) are sometimes the only availa
Paired genomic analysis of squamous cell carcinoma transformed from EGFR-mutated lung adenocarcinoma
Autor:
Youjin Kim, Boram Lee, Sehhoon Park, Jong-Mu Sun, Keunchil Park, Joon Ho Shim, Jin Seok Ahn, Woong-Yang Park, Se-Hoon Lee, Inju Cho, Yoon-La Choi, Myung-Ju Ahn, Joungho Han
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 134
Objectives Adenocarcinoma (ADC) to squamous cell carcinoma (SCC) transformation (AST) is reported in epidermal growth factor receptor (EGFR)-mutated non–small cell lung cancer after tyrosine kinase inhibitor (TKI) failure. However, little is known
Autor:
Akinori Iwasaki, Masayo Yoshimura, Tomoyuki Hida, Yoshinao Oda, Shinji Matsumoto, Yoshiaki Kinoshita, Makoto Hamasaki, Kazuki Nabeshima
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 130
Objective Malignant pleural mesothelioma (MPM) is an aggressive neoplasm with poor prognosis. Loss of BRCA-associated protein 1 (BAP1) protein expression as detected by immunohistochemistry (IHC) and homozygous deletion (HD) of the 9p21 locus as dete
Autor:
Hui Sun, Meng Wang, Feng Wang, Kaiyuan Jin, Xuemei Zhang, Tingting Huang, Bangguo Li, Xianli Luo
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 130
To explore the correlation between dual source computed tomography perfusion imaging (CTPI) and microvascular parameters, and evaluate the value of CTPI in the differential diagnosis of solitary pulmonary nodule (SPN).65 consecutive patients with SPN