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Autor:
Vanathi Sivasubramaniam, Michael Boyer, Rina Hui, Jia Liu, Prunella Blinman, Jenny H. Lee, Nick Pavlakis, Stephen Clarke, Anthony J. Gill, Steven Kao, Winny Varikatt, Wendy A Cooper, Malinda Itchins, Megan B Barnet, Madhawa De Silva, Bo Gao, Alexander E. Davis, Adnan Nagrial, Kenneth Lee
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 155
Predictive biomarkers for poor response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is an area of ongoing research. This multicentre retrospective study sought to determine the impact of programmed death-ligand 1 (PD-
Autor:
Liron Pantanowitz, Douglas J. Hartman, Humberto E. Trejo Bittar, Jacob A. Jerome, Mitra Mehrad, Sanja Dacic
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 143
Objectives Staging of non-small cell lung carcinoma associated with scar is not discussed in detail in the current American Joint Committee on Cancer staging manual. The recommendation is to include the scar area in the tumor size measurement unless
Autor:
Kentaro Imai, Morihito Okada, Norihiko Ikeda, Yoshihiro Miyata, Hiroyuki Ito, Yasuhiro Tsutani, Masaoki Ito, Haruhiko Nakayama
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 141
Recurrence risk of resected lung adenocarcinoma is represented by pathological stage (pStage), histological subtype, and potentially by EGFR mutation. However, the relationship among these factors and their combined impact on prognosis are unclear.Us
Autor:
Hojoong Kim, Byung Woo Jhun, Jungho Han, Sun Hye Shin, Hongseok Yoo, Sang-Won Um, Jhingook Kim, O Jung Kwon, Kyungjong Lee, Kyung Soo Lee, Byeong-Ho Jeong
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 139
Objectives Recent practice guidelines recommend endosonography for patients with radiological N0 non-small cell lung cancer (NSCLC) when the primary tumors are >3 cm in diameter or centrally located. However, any role for endosonography remains debat
Autor:
Ye Li, Lin Wu, Qian Chu, Zheng-Bo Han, Gen Lin, Wen-Zhao Zhong, Yi-Long Wu, Fan Yang, Bo Zhu, Hong-Mei Zhang, Jinliang Wang, Jie Hu, Meng-Xia Li, Jia-Tao Zhang, Li-Xu Yan, Huijuan Wang, Zhengfei Zhu, Xiao-Rong Dong, C. Xu, Zhengbo Song, Jie Lin, Zong-Yang Yu
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 139
Objectives The 2015 World Health Organization classification defines pulmonary large-cell neuroendocrine carcinoma (LCNEC) as a high-grade neuroendocrine carcinoma. However, the clinical characteristics and prognostic factors of pure LCNEC and combin
Autor:
Tomoyuki Yokose, Kouzo Yamada, Rurika Hamanaka, Hiroyuki Ito, Takuya Nagashima, Haruhiko Nakayama, Joji Samejima, Masaki Suzuki, Munetaka Masuda
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 137
The prognostic significance of blood and lymphatic vessel invasion in the 8th edition of the Tumor, Node, Metastasis (TNM) classification remains unclear. Therefore, this study aimed to evaluate the prognostic significance of blood and lymphatic vess
Autor:
Sonja Kobinger, Florian Eichhorn, Thomas Muley, Laura V. Klotz, Martin E. Eichhorn, Harland S. Winter
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 138
Objective Lymph node (LN) metastases predict survival in patients with non-small cell lung cancer (NSCLC) treated with curative surgery. Nevertheless, prognostic differences within the same nodal (N) status have been reported. Consequently, the Inter
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 137
Objective Histologic types are correlated with prognosis in lung adenocarcinoma. The acinar/papillary type is most common, although this group comprises heterogeneous tumor types. However, the prognostic factors in this group have not been well studi
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 136
Objective Though the possibility of using malignant pleural effusions (MPEs) as alternatives for tumor tissues in epidermal growth factor receptor (EGFR) mutation test has been examined, the diagnosis of MPE is often clinically challenging, especiall
Autor:
Zhonghua Xu, Chang Chen, Yongbing Chen, Yongsheng Zhang, Junmiao Wen, Donglai Chen, Xiaofan Wang, Qifeng Ding
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 134
To further investigate the relationship between the cribriform component and spread through air spaces (STAS), and to unravel the potential pathological mechanism of poor prognoses in lung adenocarcinoma (LUAD) patients with a cribriform component.We