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Publikováno v:
Lung Cancer. 142:13-19
Objectives This study is aimed to analyze the survival differences among patients with lung basaloid squamous cell carcinoma (BSCC), keratinizing squamous cell carcinoma (KSCC), and nonkeratinizing squamous cell carcinoma (NKSCC), and explore the pro
Autor:
Jacob Sands, Geoffrey R. Oxnard, Pasi A. Jänne, Frank C. Kuo, Adrian G. Sacher, Tom C. Nguyen, Lynette M. Sholl, Michael Cheng, Priyanka Shivdasani, Ryan S. Alden
Publikováno v:
Lung Cancer. 140:35-41
Objectives Potentially targetable genomic alterations have been identified in lung squamous cell carcinoma (LUSC), but none have yet translated into effective therapy. We examined potential benefits of next generation sequencing (NGS) in a cohort of
Autor:
Takashi Seto, Kazuki Takada, Mototsugu Shimokawa, Yoshihiko Maehara, Akira Haro, Atsushi Osoegawa, Yoshinao Oda, Tetsuzo Tagawa, Kenichi Kohashi
Publikováno v:
Lung Cancer. 128:26-32
Objectives Combination therapy with an inhibitor of indoleamine 2, 3-dioxygenase 1 (IDO1) and an agent targeting programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) is expected to be a novel and effective treatment option for variou
Publikováno v:
Lung Cancer. 104:106-110
The histological subtypes by peripheral tumor location remain uncharacterized in COPD patients with emphysema. We investigated histologic subtypes of peripheral lung cancers based on the context of heterogeneous emphysema distribution in patients wit
Autor:
Marius Lund-Iversen, Aleksandra Silye Hoven, Åslaug Helland, Odd Terje Brustugun, Steinar Solberg, Fred R. Hirsch, Marc Kevin Mcgowan
Publikováno v:
Lung Cancer. 103:52-57
Objectives Mutation in the PIK3CA gene is reported frequent in squamous cell carcinomas of the lung, but its potential prognostic role is still obscure. We have studied the prognostic importance of PIK3CA mutations as well as the relation to other ma
Publikováno v:
Lung Cancer. 85:53-58
To evaluate the efficacy of (18)F-FDG PET/CT in depicting metastatic mediastinal lymph nodes in patients with lung squamous-cell carcinoma (LSCC) or lung adenocarcinoma (LAC) in a tuberculosis-endemic country.This study retrospectively reviewed patie
Autor:
Coralie Barbe, Christine Gilles, Gonzague Delepine, Sarah Lemaire, Myriam Polette, Philippe Birembaut, Eymeric Lagonotte, Maryline Dauphin, B. Nawrocki-Raby
Publikováno v:
Lung Cancer. 81:117-122
Epithelial-to-mesenchymal transition (EMT) is believed to contribute to tumour invasion. Vimentin expression by carcinoma cells is a largely recognized marker of EMT. This study aimed at examining vimentin expression in non small cell lung carcinomas
Autor:
Masakazu Yanagi, Naoya Yokomakura, Takuya Kato, Suminori Akiba, Masami Sato, Tsutomu Hamada, Hiromasa Inoue, Noureen Khan, Takuya Samukawa, Shoji Natsugoe, Chihaya Koriyama, Takeshi Otsuka
Publikováno v:
Lung Cancer. 78:144-147
Our previous study reported a frequent detection of human papillomavirus (HPV) genome in primary lung adenocarcinomas of the recurrent patients who were responsive to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, suggesting that
Autor:
Anthony V. D'Amico, Eugenio Martinelli, D. Consoli, Rosamaria Capuano, Marco Santonico, Gabriele Lucantoni, G. La Delfa, Giovanni Galluccio, Roberto Paolesse, Giorgio Pennazza, C. Di Natale, C. Roscioni
Publikováno v:
Lung Cancer. 77:46-50
Lung cancer diagnosis via breath analysis has to overcome some issues that can be summarized by two crucial points: (1) further developments for more performant breath sampling technologies; (2) discovering more differentiated volatile fingerprints t
Autor:
Kenzo Hiroshima, Kiyoshi Shibuya, Taiki Fujiwara, Maha M. El-Kholy, Yukio Nakatani, Ichiro Yoshino, Hidehisa Hoshino, Hironobu Wada, Shigetoshi Yoshida, Tarek Mahfouz, Mohamed Alaa Rm, Makoto Suzuki, Aliae Mohamed-Hussein
Publikováno v:
Lung Cancer. 72:303-308
Objectives To assess risk of lung cancer (LC) in patients with preinvasive bronchial lesions and to identify factors associated with higher risk. Methods 124 patients with one or more preinvasive bronchial lesions and normal chest computed tomography