Zobrazeno 101 - 110
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Autor:
Dario Consonni, Agostino Cortelezzi, Gianluigi Reda, Silvia Lonati, Wilma Barcellini, Alberto Zanella, Lucia Nobili, Bruno Fattizzo, Francesca Guia Imperiali, Anna Zaninoni
Publikováno v:
Leukemialymphoma. 55(8)
Toll-like receptors (TLRs) represent major agents of innate immunity and initiators of adaptive immunity. TLR4 and TLR9 gene expression was related to the occurrence of infections, autoimmunity and disease progression in 95 patients with B-chronic ly
Autor:
Sameer Bakhshi, Vinod Raina, Sandeep Mathur, Atul Sharma, Asis Kumar Karak, Lalit Kumar, Smita Kayal
Publikováno v:
Leukemialymphoma. 55(5)
A novel biomarker, CD68, which marks tumor-associated macrophages (TAMs) in the microenvironment, has recently been reported to affect the prognosis of Hodgkin lymphoma (HL). We aimed to evaluate its role in our patient cohort (n = 100) by utilizing
Autor:
Nathalie Nols, Anne Sonet, Thierry Vander Borght, Eric Van Den Neste, Lucienne Michaux, Nicolas Mounier, André Bosly, Marc André, Marie-Christiane Vekemans, S. Costantini, Renaud Lhommel, Salima Bouazza
Publikováno v:
Leukemialymphoma. 55(4)
The prognostic value of interim (18)fluorodeoxyglucose positron emission tomography (i-PET) was investigated in 73 patients (median age 60 years) with diffuse large B-cell lymphoma (DLBCL). i-PET was analyzed using the Deauville score (DS) and change
Autor:
Henrik J. Ditzel, Michael Boe Møller, Lars Melholt Rasmussen, Ida Bruun Kristensen, Niels Abildgaard, Lise Pedersen, Jacob Haaber Christensen, Maria Bibi Lyng
Publikováno v:
Kristensen, I B, Christensen, J H, Lyng, M B, Møller, M B, Pedersen, L M, Rasmussen, L M, Ditzel, H J & Abildgaard, N 2014, ' Expression of osteoblast and osteoclast regulatory genes in the bone marrow microenvironment in multiple myeloma : only up-regulation of Wnt inhibitors SFRP3 and DKK1 is associated with lytic bone disease ', Leukemia and Lymphoma, vol. 55, no. 4, pp. 911-919 . https://doi.org/10.3109/10428194.2013.820288
Multiple myeloma (MM) lytic bone disease (LBD) is caused by osteoclast activation and osteoblast inhibition. RANK/RANKL/OPG play central roles in osteoclast activation and Wnt inhibitor DKK1 in osteoblast inhibition. The role of other Wnt inhibitors
Autor:
Mariana Bleker de Oliveira, Sang W. Han, Laurent Knoops, Fernanda C. Corbi, Vania M. Morelli, Jean-Christophe Renauld, Gisele W. B. Colleoni
Publikováno v:
Leukemia & Lymphoma, Vol. 55, no. 5, p. 1176-1180 (2014)
Considering the recent impact of tyrosine kinase inhibitors in the treatment of myeloproliferative disorders carrying a recurrent JAK2 mutation not identified in multiple myeloma (MM), this study aimed to search for mutations in kinase and pseudokina
Autor:
Margaret L. Pfeiffer, Jorge E. Romaguera, Nathan Fowler, Felipe Samaniego, Bita Esmaeli, Qasiem J. Nasser, Mathieu F. Bakhoum, Tarek El-Sawy, Peter McLaughlin, J. Matthew Debnam
Publikováno v:
Leukemialymphoma. 55(5)
The objective of this study was to assess the value of magnetic resonance imaging (MRI) of the orbit for conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma. The yield of other staging tests at baseline were also evaluated. Twenty-one cons
Publikováno v:
Leukemialymphoma. 55(3)
Methotrexate (MTX), a folate antagonist employed for treating a wide range of malignancies, has an extensive interpatient variability, resulting in unpredictable toxicity. The present study evaluated the impact of single gene polymorphisms (SNPs: rs1
Publikováno v:
Leukemialymphoma. 55(5)
Genetic and environmental factors are involved in the pathogenesis of non-Hodgkin lymphoma (NHL). The present study aimed to investigate the association between cytotoxic T-lymphocyte antigen 4 (CTLA-4) genetic polymorphism, hepatitis C virus (HCV) i
Autor:
Andy K Hsu, David Ritchie, Paula Savage, Martha Li, Paul J Neeson, H. Miles Prince, Anna Sureda, Anas Younes, Margaret Squier, Andreas Engert, Roberto Bugarini, Denise Williams, Simon J. Harrison
Publikováno v:
Leukemialymphoma. 55(5)
In a phase 2 trial of panobinostat in 129 patients with relapsed or refractory Hodgkin lymphoma, exploratory analyses of chemokines and cytokines were prospectively performed in 109 patients to determine their association with clinical outcomes. Pati
Autor:
Milada Jankovska, Marek Trněný, Samuel Vokurka, Pavla Veselá, David Šálek, Michal Michal, Ludmila Boudova, Andrea Janíková, Jiri Mayer, Jan Pirnos, Eva Janoušová, Robert Pytlik, Roman Kodet, Mojmír Moulis, Jan Muzik, David Belada, Pavel Klener
Publikováno v:
Leukemialymphoma. 55(4)
Although a prognostic model (MIPI, Mantle Cell Lymphoma International Prognostic Index) for patients with mantle cell lymphoma (MCL) has been established, its clinical significance for daily practice in the rituximab era remains controversial. Data o