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Autor:
Vladimir Bumbasirevic, Bosko Andjelic, Ljubomir Jakovic, Maja Perunicic Jovanovic, Andrija Bogdanovic, Dragan Babić, Biljana Mihaljevic
Publikováno v:
Leukemialymphoma. 57(8)
We studied the prognostic significance of the absolute lymphocyte/monocyte count ratio (ALC/AMC), its contribution to the prognostic value of the International Prognostic Score (IPS), and evaluated if ALC/AMC could serve as a proxy for the frequency
Autor:
Sehui Kim, Wook Youn Kim, Chul Woo Kim, Yoon Kyung Jeon, Tae Min Kim, Dae Seog Heo, Soo Jeong Nam
Publikováno v:
Leukemialymphoma. 56(6)
Extranodal natural killer/T-cell lymphoma (NKTCL) has aggressive behaviors and poor clinical outcomes. A monomethyl auristatin E-conjugated anti-CD30 antibody (brentuximab vedotin) was recently introduced to treat CD30-positive lymphomas. Thus we inv
Autor:
Gregory M. Cote, Robert A. Redd, Ann S. LaCasce, Donna Neuberg, Olga Pozdnyakova, Ephraim P. Hochberg, Arnold S. Freedman, David M. Dorfman, David C. Fisher, Paola Dal Cin, Eric D. Jacobsen, Ali Shahsafaei, Philippe Armand, Jennifer R. Brown
Publikováno v:
Leukemialymphoma. 56(4)
Platelet derived growth factor-α (PDGFR-α) is expressed in peripheral T cell lymphoma, not otherwise specified (PTCL, NOS). Imatinib mesylate demonstrated in vitro cytotoxicity against primary PTCL, NOS cells. We initiated a trial of imatinib in 12
Autor:
Stephen D. Smith, Brian J. Bolwell, Anjali S. Advani, Steven W. Andresen, Josephine L. Chan, Robert M. Dean, Eric D. Hsi, Matt E. Kalaycio, Brad L. Pohlman, Lisa A. Rybicki, John W. Sweetenham
Publikováno v:
Leukemialymphoma. 50(10)
Transformed lymphoma (TL) is historically associated with a poor prognosis, though autologous stem cell transplantation (ASCT) has been applied successfully. Better patient selection is needed for this intensive therapy. We analyzed the outcomes betw
Autor:
Claudio Chini, Graziella Pinotti, Ilaria Proserpio, Silvia Marchet, Claudia Placidi, Silvia Uccella, Raffaele Novario, Massimiliano Cergnul, Carlo Capella
Publikováno v:
Leukemialymphoma. 49(7)
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease. The immunohistochemistry-based algorithms for the determination of the cell of origin of DLBCL have been proposed as a practical method to validate and surrogate results obtained by ge
Autor:
Evert M. Noordijk, E. Maartense, Philippus Kluin, S. le Cessie, M. H. H. Kramer, S. Snijder, Johanna Kluin-Nelemans
Publikováno v:
Leukemia and Lymphoma, 45(1), 101-107. TAYLOR & FRANCIS LTD
The prognostic significance of age was studied in 372 patients with diffuse large B-cell non-Hodgkin's lymphoma, in relation to the prognostic factors of overexpressed BCL2 and p53 oncoprotein. Overexpression of BCL2 and p53 oncoprotein was defined w
Publikováno v:
Leukemialymphoma. 42(3)
We have previously described a relation between abundance of eosinophilic granulocytes in Hodgkin's disease (HD) tumours and poor prognosis. In order to further explore the importance of the eosinophilic infiltration, we immunohistochemically examine
Autor:
Andreas H. Sarris, Fernando Cabanillas, L. J. Medeiros, V. Bonfante, Roberto Giardini, George Z. Rassidakis, S. Viviani, S. W. Morris, M. Gianni, Marco Herling
Publikováno v:
Scopus-Elsevier
The t(2;5)(p23;q35) or other rare chromosomal abnormalities involving 2p23 upregulate the ALK gene, which is not expressed in normal lymphocytes. Thus, detection of ALK protein is presumptive evidence of these 2p23 abnormalities. The t(2;5) and ALK i