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Epidemiology, longitudinal treatment patterns and outcomes of chronic lymphocytic leukemia in Israel
Autor:
Yair Herishanu, Inna Kan, Clara Weil, Kavita Sail, Ran Afik, Varda Shalev, Raanan Cohen, Gabriel Chodick
Publikováno v:
Leukemialymphoma. 62(5)
This study aims to describe chronic lymphocytic leukemia (CLL) epidemiology, treatment patterns and outcomes in a 2.3-million-member healthcare provider database (Maccabi Healthcare Services, Israel). Newly-diagnosed CLL patients (1999-2017) were fol
Autor:
Anoop K Enjeti, Naomi Mackinlay, Eva Yip, Luke Coyle, William Stevenson, Vicki Katsioulas, Christopher Arthur, Jake Shortt, Keith Fay, Matthew Greenwood, Anastasios Nalpantidis, Anthony Jeffrey, Ian Kerridge
Publikováno v:
Leukemialymphoma. 61(4)
The prognosis of AML in elderly patients is poor and research into novel therapeutic approaches is urgently needed. This study examined the use of low-dose chemotherapy with cytarabine and thioguanine administered in repetitive cycles in 62 elderly p
Autor:
Xinyi Lin, Fei Qi, Shunan Qi, Shulian Wang, Yongwen Song, Shengyu Zhou, Jianliang Yang, Hui Fang, Yexiong Li, Mei Dong, Bo Chen, Sheng Yang, Lin Gui, Jingjing Wang, Peng Liu
Publikováno v:
Leukemialymphoma. 60(11)
Early/upfront radiation was associated with improved survivals compared with late radiation for early-stage NK/T-cell lymphoma (NKTCL) in the old era when anthracycline-base chemotherapy (CT) prevailed. However, in the modern era of effective l-aspar
Autor:
Hervé Dombret, Simon Durrant, Christopher Larry Bacon, Qui Tran, Max S. Topp, Andre C. Schuh, Zachary Zimmerman, Hagop M. Kantarjian, Andrew H. Wei
Publikováno v:
Leukemialymphoma. 60(9)
Outcomes for adults with relapsed/refractory acute lymphoblastic leukemia (ALL) are poor with chemotherapy, particularly in later salvage. The TOWER study examined survival, remission, bridge to allogeneic hematopoietic stem cell transplantation (HSC
Autor:
Gregory F. Guzauskas, Per-Olof Thuresson, Keith L Dawson, David L. Veenstra, Anthony Masaquel
Publikováno v:
Leukemialymphoma. 60(7)
The GALLIUM trial compared obinutuzumab (GA101, G)-based chemotherapy followed by G monotherapy (G + chemo) for up to two years to rituximab (R)-based chemotherapy followed by R monotherapy (R + chemo) for up to two years in previously untreated foll
Autor:
Frédéric Pène, Antoine Rabbat, Dominique Benoit, Michael Darmon, Elie Azoulay, Christine Lebert, François Vincent, Anne-Pascale Meert, Fabrice Bruneel, Pierre Perez, Achille Kouatchet, Xavier Mignard, Lara Zafrani, Lucie Biard, Rebecca Hamidfar, Virginie Lemiale, Martine Nyunga, Julien Mayaux, Djamel Mokart
Publikováno v:
Leukemialymphoma. 60(5)
In patients with hematologic malignancies, respiratory status may deteriorate during neutropenia recovery. This multicenter, observational study aims to evaluate granulocyte colony-stimulating factor (G-CSF) impact on respiratory status in critically
Combination immunotherapy as a non-chemotherapy alternative for refractory or recurrent CNS lymphoma
Autor:
Tricia White, Edward A. Neuwelt, Kirsten Johansson, Laszlo Szidonya, Nancy D. Doolittle, Prakash Ambady, Jessica James, Caroline Jezierski, Jenny Firkins
Publikováno v:
Leukemialymphoma. 60(2)
Primary central nervous system lymphoma (PCNSL) is an extemely rare, CD20+ non-germinal center B cell lymphoma (diffuse large cell type) in a bed of T-cell rich tumor microenvironment. The prognost...
Autor:
Claire Dearden, Kim Linton, Michael Potter, John Radford, Patrick Shenjere, Kate Foley, Clare Peckitt, Ian Chau, Lia P Menasce, Mark Ethell, Catherine O'Hara, Hannah Johnson, Andrew Wotherspoon, Binnaz Yasar, David Cunningham, Ayoma D. Attygalle, Adam Gibb, Rebecca Lee, Joanna Dash, Mary Gleeson, Eliza A Hawkes, Morgan Back
Publikováno v:
Leukemialymphoma. 59(7)
We evaluated the outcomes for patients with peripheral T-cell lymphoma (PTCL) undergoing front-line chemotherapy at our institutions between 2002 and 2012. One hundred and fifty-six patients were eligible, comprising PTCL not otherwise specified (NOS
Autor:
Joseph M. Connors, Laurie H. Sehn, Cynthia L. Toze, Steven J.T. Huang, Heather A. Leitch, Alina S. Gerrie, Helene Bruyere, Khaled M. Ramadan, Lauren J. Lee, Tanya L Gillan
Publikováno v:
Leukemialymphoma. 59(6)
Chemoimmunotherapy with rituximab improves survival in clinical trials in upfront chronic lymphocytic leukemia (CLL) treatment. This study compared clinical outcomes with and without rituximab added to first-line chemotherapy in a provincial cohort o
Autor:
Lara Mannelli, Luigi Rigacci, Benedetta Puccini, S. Kovalchuk, Monica Bocchia, Emanuele Cencini, T. Carfagno, Alberto Bosi, Gabriele Simontacchi, Alberto Fabbri, Gemma Benelli
Publikováno v:
Leukemialymphoma. 59(6)
Early-stage follicular lymphoma (FL) can be cured with involved-field radiotherapy (IF-RT); however, many patients relapse in non-irradiated areas. A combined association with chemotherapy could increase treatment efficacy, but toxic effects could be