Zobrazeno 51 - 60
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Autor:
Bjørn Østenstad, Jan Delabie, Martin Erlanson, Christer Sundström, Peter de Nully Brown, Karin Fahl Wader, Hans Hagberg, Tomas Ahlgren, Ola Lindén, Ann-Sofie Johansson, Björn E. Wahlin, Harald Holte, Eva Kimby
Publikováno v:
Leukemialymphoma. 56(9)
Patients with advanced CD20 + indolent lymphoma, requiring therapy, were randomized to rituximab (four weekly infusions of 375 mg/m(2)) or to rituximab combined with 5 weeks of interferon-α2a (IFN-α2a) (3-4.5 MIU daily) as priming. Responding patie
Autor:
Krzysztof Giannopoulos, Waldemar Tomczak, Paulina Wlasiuk, Maciej Grzywnowicz, Katarzyna Skorka, Irena Frydecka, Joanna Zaleska, Agnieszka Bojarska-Junak, Anna Dmoszynska, Sylwia Chocholska, Agnieszka Karczmarczyk, Lidia Karabon, Malgorzata Zajac
Publikováno v:
Leukemialymphoma. 56(10)
Programmed death-1 (PD-1) is a negative receptor expressed on lymphocytes including malignant B cells in chronic lymphocytic leukemia (CLL). In this work, we found that patients with CLL had a higher expression of PD-1 transcript (PDCD1) than healthy
Autor:
Diane M. Banks, Michael K. Keng, Paul Elson, Jaroslaw P. Maciejewski, Moshe Chaim Ornstein, Mikkael A. Sekeres, Anjali S. Advani, Sudipto Mukherjee, Madeline Schaub, Ramon V. Tiu, Matt Kalaycio, Yogen Saunthararajah, Amanda L. Maggiotto
Publikováno v:
Leukemialymphoma. 56(9)
This study aimed to identify the rate and impact of vancomycin-resistant enterococcal (VRE) bacteremia in patients with acute myeloid leukemia (AML) receiving induction chemotherapy (IC). Thirty-seven (10.6%) of 350 patients had VRE bacteremia during
Autor:
Pau Abrisqueta, Coumaran Egile, Frauke Bentzien, Drew W. Rasco, Jason Jiang, Julie M. Vose, Kyriakos P. Papadopoulos, Josep Tabernero, Rodrigo Ruiz-Soto, Weiliang Shi
Publikováno v:
Leukemialymphoma. 56(6)
The maximum tolerated dose of SAR245409 (voxtalisib), a pan-class I phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor, was determined in a phase 1 dose-escalation study in advanced solid tumors. We report safety, pha
Autor:
Sehui Kim, Wook Youn Kim, Chul Woo Kim, Yoon Kyung Jeon, Tae Min Kim, Dae Seog Heo, Soo Jeong Nam
Publikováno v:
Leukemialymphoma. 56(6)
Extranodal natural killer/T-cell lymphoma (NKTCL) has aggressive behaviors and poor clinical outcomes. A monomethyl auristatin E-conjugated anti-CD30 antibody (brentuximab vedotin) was recently introduced to treat CD30-positive lymphomas. Thus we inv
Autor:
Veronica Verri, Yamila Sieza, Raquel Bengió, Myriam Attie, Irene Larripa, Yesica Soledad Bestach, Cecilia Riccheri, Moira Bolesina, Carolina Bárbara Belli
Publikováno v:
Leukemialymphoma. 56(6)
The impaired hematopoiesis in acquired aplastic anemia (AA) results from immune-mediated mechanisms. We characterized polymorphisms implicated in controlling type-1 cytokine production in 69 patients with AA. Our data suggest that the studied polymor
Publikováno v:
Leukemialymphoma. 56(6)
Human T-lymphotropic virus type 1 (HTLV-1) is highly endemic in the Kyushu/Okinawa region of Japan. A nationwide investigation verified the frequency of HTLV-1 carriers among first-time blood donors and the occurrence of newly diagnosed adult T-cell
Autor:
Ariel Agur, Eldad J. Dann, Neta Goldschmidt, Gail Amir, Hanoch Goldschmidt, Ora Paltiel, Martine Klein
Publikováno v:
Leukemialymphoma. 56(5)
The prognostic role of CD68 tumor-associated macrophages in classic Hodgkin lymphoma (cHL) remains controversial. We stained diagnostic biopsies and scored for CD68 using the PGM1 antibody among 98 consecutive patients with cHL from our center follow
Autor:
Tim Tristan Hardel, Harald Biersack, Dirk Rades, Alfred C. Feller, Christoph Thorns, Niklas Gebauer, Judith Gebauer, Hendrik Lehnert, Veronica Bernard
Publikováno v:
Leukemialymphoma. 56(4)
Epstein-Barr virus (EBV)-associated diffuse large B-cell lymphoma (DLBCL) of the elderly constitutes a provisional clinicopathological entity in the current World Health Organization (WHO) classification and its genomic features remain sparsely chara
Autor:
Run Zhang, Li Wang, Cheng Fang, Li Na Zhang, Wei Xu, Lei Fan, Ken H. Young, Zhi Jian Zou, Jianyong Li
Publikováno v:
Leukemialymphoma. 56(3)
The purpose of this study was to investigate the significance of polymorphisms in the CD20 gene in patients with diffuse large B-cell lymphoma (DLBCL). We sequenced exons 3-8 in 160 patients with de novo DLBCL and detected the expression of CD20 via