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Autor:
Nicolas van Baren, Pascale Saussoy, Marie-Sophie Dheur, Pierre Coulie, Eric Van Den Neste, Jean-Philippe Defour, Gaëlle Tilman, Hélène Poirel, Geneviève Ameye, Alessandra Camboni
Publikováno v:
Leukemia & lymphoma, Vol. 60, no. 4, p. 1043-1052 (2019)
High-grade B-cell lymphomas with MYC and BCL2 or BCL6 rearrangements are highly aggressive B-cell lymphomas called double-hit lymphomas (HGBL-DH). They are particularly refractory to standard treatments and carry a poor prognosis. Fragments of resect
Autor:
Dido Lenze, Korinna Jöhrens, Ioannis Anagnostopoulos, Marita Ziepert, Michael Hummel, Michael Pfreundschuh, Ralf Ulrich Trappe
Publikováno v:
Leukemialymphoma. 57(12)
We investigated 41 diffuse large B-cell lymphomas (DLBCL) diagnosed at one center harboring ≥50% of latently Epstein–Barr virus (EBV)-infected neoplastic cells occurring in 34 patients aged ≥50 years and in 7 patients younger than 50 years in t
Autor:
Tim Tristan Hardel, Harald Biersack, Dirk Rades, Alfred C. Feller, Christoph Thorns, Niklas Gebauer, Judith Gebauer, Hendrik Lehnert, Veronica Bernard
Publikováno v:
Leukemialymphoma. 56(4)
Epstein-Barr virus (EBV)-associated diffuse large B-cell lymphoma (DLBCL) of the elderly constitutes a provisional clinicopathological entity in the current World Health Organization (WHO) classification and its genomic features remain sparsely chara
Autor:
Claudio A. Mosse, Annette S. Kim, Mary M. Zutter, Edward R. Marx, Adam C. Seegmiller, Megan K. Kressin, Allison Wasserman
Publikováno v:
Leukemialymphoma. 55(3)
Fluorescence in situ hybridization for abnormalities common to myelodysplastic syndrome (MDS FISH) is often used with traditional karyotype in the diagnosis and monitoring of myeloid neoplasms. However, its value in these roles has been questioned. T
Autor:
María José Herranz, Sergi Serrano, Beatriz Bellosillo, Ana B. Galván, Anna Puiggros, Ana Ferrer, Lara Nonell, María Rodríguez-Rivera, Silvia Pairet, Eva Gimeno, Eulàlia Puigdecanet, Eugenia Abella, Lourdes Florensa, Blanca Espinet, Marta Salido, Carme Melero, Francesc Solé
Publikováno v:
Leukemialymphoma. 54(5)
Chronic lymphocytic leukemia (CLL) is characterized by a highly variable clinical course. Del(11q) and del(17p), routinely studied by conventional G-banding cytogenetics (CGC) and fluorescence in situ hybridization (FISH), have been related to progre
Publikováno v:
Leukemialymphoma. 53(12)
In this study we assessed the prognostic value of amp(1q21) alone and in combination with del(17p13), del(13q14) and t(4,14)(p16;q32) detected by fl uorescence in situ hybridization(FISH) in newly diagnosed patients with MM treated with thalidomide-b
Publikováno v:
Leukemialymphoma. 53(3)
Rapid and accurate detection of BCR-ABL fusion proteins is vital for the diagnosis and classification of leukemias, especially chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). Recently, the cytometric bead array (CBA) system has
Autor:
Antonino Carbone, Maria Grazia Tibiletti, Annunziata Gloghini, Diego Rossi, Barbara Bernasconi, Tiziana Perin, Vincenzo Canzonieri
Publikováno v:
Leukemialymphoma. 53(4)
In situ follicular lymphoma (FL) is usually an incidental finding in otherwise reactive lymph node. This report describes two cases of lymph nodal in situ FL complicated by the association with nonlymphoid neoplasms. In case 1, in situ FL was discove
Autor:
Johana Meléndez-Santiago, Alan F. List, Jeffrey E. Lancet, Jong Y. Park, Hyun Park, Jeffrey S. Painter, Pearlie K. Epling-Burnette, William J. Fulp, Rami S. Komrokji, Dana E. Rollison, Ji-Hyun Lee, Kristen A. Jonathan, Ashley L. Cole, Mayenha Guerrier
Publikováno v:
Leukemialymphoma. 52(8)
The relationship between telomere length (TL) and predisposition to myelodysplastic syndromes (MDS) remains unclear. We compared peripheral blood leukocyte (PBL) TL among cases of histologically confirmed MDS (n = 65) who were treatment-naive with no
Autor:
Dai Maruyama, Takashi Watanabe, Yoshinori Kawabata, Hirokazu Taniguchi, Kensei Tobinai, Yukio Kobayashi, Junko Nomoto, Kenji Yamada, Akiko Miyagi Maeshima, Sung-Won Kim, Hitoshi Tsuda
Publikováno v:
Leukemialymphoma. 52(5)
We report four cases of exceptional follicular lymphoma (FL) showing marked monocytoid or plasmacytoid differentiation and tiny or indistinct follicles, mimicking marginal zone lymphoma or plasma cell neoplasm. The lymphoma of patient 2 had lymphoepi