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Autor:
Arinobu Tojo, Masamichi Isobe, Seiko Kato, Takaaki Konuma, Mai Mizusawa, Kazuaki Yokoyama, Maki Oiwa-Monna, Satoshi Takahashi
Publikováno v:
Leukemialymphoma. 60(9)
Genetic mutation is one of the most powerful prognostic factors for adult patients with acute myeloid leukemia (AML). The FMS-like tyrosine kinase 3 (FLT3) gene mutations, including internal tandem...
Autor:
Kentaro Narita, Kosei Matsue, Manabu Fujisawa, Masami Takeuchi, Kota Fukumoto, Yasuto Suehara, Yoshiaki Usui
Publikováno v:
Leukemialymphoma. 57(8)
To investigate the impact of immunophenotypic complete response [iCR, ≤10(-4) multiple myeloma (MM) cells defined by multicolor flow cytometry (MFC)] on survival in patients with MM, we retrospectively analyzed 78 patients that obtained conventiona
Publikováno v:
Leukemialymphoma. 57(7)
One of the severe toxicities of pegaspargase (PEG) is the development of allergic reactions. This study retrospectively assessed 311 PEG doses administered to 139 acute lymphoblastic leukemia patients from May 1, 2008 to July 30, 2014 for allergic re
Autor:
Heba Hashem, Suhaib A. Radi, Mohammed Ali Alshehri, Mohammed Burhan Abrar, Mohammed A Abdelaal, Enaam Alsobhi, Ahmed Absi, Zayed Alzahrani, Ashraf Warsi, Ihab El-Hemaidi, Ahmed Alsaeed, Abdulfattah Al-Amri, Hanadi Shiekhi, Safaa Bayashoot, Anas Merdad
Publikováno v:
Leukemialymphoma. 56(4)
No study has been published yet in the Arab world regarding response and outcome of imatinib in patients with chronic myeloid leukemia (CML). This study evaluated a total of 122 patients with CML treated with imatinib between 2001 and 2012. Survival,
Autor:
Run Zhang, Li Wang, Cheng Fang, Li Na Zhang, Wei Xu, Lei Fan, Ken H. Young, Zhi Jian Zou, Jianyong Li
Publikováno v:
Leukemialymphoma. 56(3)
The purpose of this study was to investigate the significance of polymorphisms in the CD20 gene in patients with diffuse large B-cell lymphoma (DLBCL). We sequenced exons 3-8 in 160 patients with de novo DLBCL and detected the expression of CD20 via
Autor:
Ryan D. Cassaday, Andrei R. Shustov, Mary Philip, David G. Maloney, Brian G. Till, William I. Bensinger, Colin Phipps, Barry E. Storer, Edward N. Libby, Leona Holmberg, Thomas R. Chauncey, John M. Pagel, Oliver W. Press, Damian J. Green, Maria Corinna Palanca-Wessels, Ajay K. Gopal
Publikováno v:
Leukemialymphoma. 56(1)
Patients with rituximab-refractory follicular lymphoma (FL) have limited options. Before the rituximab era, autologous stem cell transplant (ASCT) was shown to improve outcomes in chemotherapy-sensitive, relapsed FL, but the impact of rituximab-sensi
Autor:
John F. Seymour, Simon J. Harrison, Max Wolf, Kerrie Stokes, Philip A. Thompson, Nicole Wong Doo, H. Miles Prince, David Ritchie, Trish Joyce, Kate Burbury
Publikováno v:
Leukemialymphoma. 54(7)
There are no uniform guidelines for the treatment of relapsed refractory multiple myeloma (MM), however autologous stem cell transplant (SCT) remains an important treatment modality. Although a number of modifications to high dose melphalan (HDM) con
Autor:
Jiri Mayer, Martina Tošková, Barbora Ziakova, Zdenek Racil, Kristina Forsterova, Julia Gabzdilova, Monika Rolencová, Lucia Masárová, Iva Kocmanová, Jan Haber, Petr Cetkovsky, Tomáš Guman, Eva Bojtárová, Lucie Burešová, Shira Timilsina, Michal Kouba, Elena Tóthová, Lubos Drgona
Publikováno v:
Leukemialymphoma. 54(5)
The objective of this retrospective, multicenter study was to evaluate the efficacy and safety of micafungin as empirical antifungal therapy during febrile neutropenia (FN) in 73 hematological patients from six centers in two countries. All patients
Autor:
Hazel Bailey, Angela C. Casbard, Stephen Gerry, Tim Maughan, Sue Wosniak, Stefan Dojcinov, Louise King, Eve Gallop-Evans, James Powell
Publikováno v:
Leukemialymphoma. 54(5)
We evaluated hypoxia inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) expression and their prognostic significance in diffuse large B-cell lymphoma (DLBCL). Expression of HIF-1α and VEGF was studied in 78 patients and res
Autor:
Fausto Rossini, Maria Elena Cabrera, Emanuele Zucca, Alessandro Rambaldi, Enrico Maria Pogliani, Elena Oldani, Andrea Rossi, Stefano Luminari, Richard W. Tsang, Annarita Conconi, Michael Mian, Mary Gospodarowicz, Massimo Federico, Sergio Cortelazzo, Maurizio Martelli, Gonzalo Gutiérrez-García, Andrés J.M. Ferreri, Mario Busetto, Franco Cavalli
Publikováno v:
Leukemialymphoma. 54(1)
Consolidation radiotherapy (cRT) in patients with stage I/II diffuse large B-cell lymphoma of the Waldeyer's ring (WR-DLBCL) in complete remission (CR) after induction chemotherapy (CHT) is often associated with relevant acute and chronic toxicity, a