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Autor:
Ritsu Sumiyoshi, Haruko Tashiro, Ryosuke Shirasaki, Takuji Matsuo, Tadashi Yamamoto, Kensuke Matsumoto, Jun Ooi, Naoki Shirafuji
Publikováno v:
Leukemia research. 113
The role of the FMS-like tyrosine kinase 3 (FLT3) gene in acute myeloid leukemia (AML) has been well documented and the FLT3-internal tandem duplication (FLT3-ITD) mutation has been identified as a prognostic factor in AML. Due to its low incidence,
Autor:
Sae Matsuoka, Takashi Ikeda, Yumiko Toda, Daisuke Minakata, Rui Murahashi, Shin-Ichiro Kawaguchi, Hirofumi Nakano, Chihiro Yamamoto, Kazuya Sato, Takashi Nagayama, Shin-ichiro Fujiwara, Kaoru Morita, Kaoru Hatano, Yoshinobu Kanda, Masahiro Ashizawa, Kiyomi Mashima, Shoko Ito, Hirotomo Nakashima, Ken Ohmine, Kento Umino, Ryoko Yamasaki
Publikováno v:
Leukemia Research. 112:106750
We retrospectively examined 57 patients with multiple myeloma who underwent autologous stem cell transplantation (ASCT) at our institution. A receiver-operating characteristic curve (ROC) analysis showed that the reduction rate of quantitative serum
Autor:
Z V Martina, N I Bilous, A Chumak, Iryna Kryachok, I. Abramenko, Iryna Dyagil, Vladimir Saenko
Publikováno v:
Leukemia Research. 58:1-8
Objectives To analyze the distribution of single nucleotide polymorphisms (SNPs) in the TP53 gene in chronic lymphocytic leukemia (CLL) patients and to evaluate their associations with clinical behavior of the disease. Methods SNPs in exons and parts
Autor:
Monica Bocchia, Antonella Geromin, Santina Sirianni, Renato Fanin, Mario Tiribelli, Daniela Damiani, Donatella Raspadori, Margherita Cavallin, Erica Simeone
Publikováno v:
Leukemia Research. 58:31-38
Overexpression of CD200, a trans-membrane protein belonging to the immunoglobulin superfamily, has been associated with poor prognosis in patients with acute myeloid leukemia (AML). As few data are available in the subset of cytogenetically-normal (C
Autor:
Abhishek A. Mangaonkar, Mark R. Litzow, Curtis A. Hanson, Aref Al-Kali, Naseema Gangat, William J. Hogan, Michelle A. Elliott, Rhett P. Ketterling, Alexandra P. Wolanskyj-Spinner, Mrinal M. Patnaik, Kebede H. Begna
Publikováno v:
Leukemia Research. 71:60-62
Introduction The 2016 World Health Organization (WHO) classification of myeloid neoplasms reclassified patients with myelodysplastic syndromes (MDS) with multilineage dysplasia (MLD) based on the presence or absence of ring sideroblasts (RS). We perf
Autor:
J. Budnik, Michael T. Milano
Publikováno v:
Leukemia research. 78
Introduction Mast cell leukemia (MCL) is rare and carries a poor prognosis. No standard-of-care has been established. No USA registry-based analyses have examined clinical correlates of overall survival (OS) in MCL patients, thus we aimed to do this
Autor:
Lata Rani, Anubha Gupta, Ritu Gupta, Nitin Mathur, Lalit Kumar, Vishwajeet Singh, Gurvinder Kaur, Om Dutt Sharma, Atul Sharma
Publikováno v:
Leukemia research. 76
Complex Chromosomal Rearrangements (CCRs) are increasingly being reported as genetic risk factors of clinical significance in cancer owing to their identification using high resolution whole genome profiling technologies. This study employed high res
Autor:
Jin-Hua Liang, Lei Cao, Xiaoyan Qu, Xiaoli Zhao, Dong-Ping Huang, Li Wang, Lei Fan, Jia-Zhu Wu, Jianyong Li, Yu-Qiong Yang, Wei Xu
Publikováno v:
Leukemia Research. 42:88-92
This study was aimed at investigating the prognostic significance of the absolute monocyte count (AMC) in peripheral blood in patients with newly diagnosed angioimmunoblastic T cell lymphoma (AITL). AMC was performed in 73 therapy-naive patients with
Autor:
Benny Johnson, Smith Giri, Omer Jamy, Michelle Tzue-e Chi, Michael Gary Martin, David W. McCormick, Vijaya Raj Bhatt
Publikováno v:
Leukemia Research. 39:1342-1346
Compared to secondary acute myeloid leukemia, secondary acute lymphoblastic leukemia (sALL) is poorly characterized. We utilized data from the Surveillance, Epidemiology, and End Results (SEER) 13 database to further elucidate patient characteristics
Autor:
Koichi Takahashi, Guillermo Garcia-Manero, Tapan M. Kadia, Zach Bohannan, Keyur P. Patel, Monica Cabrero, Elias Jabbour, Farhad Ravandi, Talha Badar, Courtney D. DiNardo, Gautam Borthakur, Raja Luthra, Sherry Pierce, Philip A. Thompson, Hagop M. Kantarjian, Jorge E. Cortes, Marina Konopleva, Naval Daver
Publikováno v:
Leukemia Research. 39:1367-1374
Background The molecular events that drive the transformation from myelodysplastic syndromes (MDS) to acute myeloid leukemia (AML) have yet to be fully characterized. We hypothesized that detection of these mutations at the time of transformation fro