Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sherif Abdelhamed"'
Autor:
Shondra M. Pruett-Miller, Melvin Edward Thomas, Jason R. Schwartz, Guangchun Song, Jing Ma, Jeffery M. Klco, Michael Walsh, Sadie Miki Sakurada, Ryan Hiltenbrand, Sherif Abdelhamed
Publikováno v:
Leukemia
Pediatric myelodysplastic syndromes (MDS) are a heterogeneous disease group associated with impaired hematopoiesis, bone marrow hypocellularity, and frequently have deletions involving chromosome 7 (monosomy 7). We and others recently identified hete
Publikováno v:
Leukemia
Successive adaptation of the bone marrow (BM) from homeostatic hematopoietic microenvironment to a self-reinforcing niche is an integral aspect of leukemogenesis. Yet, the cellular mechanisms underlying these functional alterations remain to be defin
Autor:
Johannes Elferich, Mona M.Hosseini, Sherif Abdelhamed, Jason E. McDermott, Brian J. Druker, Ujwal Shinde, Karin D. Rodland, Anupriya Agarwal, Shawn Mahmood, Samuel H. Payne, Monika A. Davare, Tao Liu, Jack W. Singer, Motomi Mori, Andy Kaempf, Stephen E. Kurtz
Publikováno v:
Leukemia. 32(11)
Interleukin-1 receptor-associated kinase 1 (IRAK1), an essential mediator of innate immunity and inflammatory responses, is constitutively active in multiple cancers. We evaluated the role of IRAK1 in acute myeloid leukemia (AML) and assessed the inh