Zobrazeno 1 - 10
of 158
pro vyhledávání: ''
Autor:
Wenbo Xu, Jingxin Li, Zhe Zhang, Wen-Jiao Yin, Guo Qiang, Li-Hua Hou, Fengcai Zhu, Xu Zhang, Wen-Juan Wang, Wei Chen, Yuemei Hu, Manal Ghazzawi, Shipo Wu, Abdul R Wurie, Qi Liang, Yu-Hua Li, Alie H Wurie, Junzhi Wang, James B W Russell, Lei Duan
Publikováno v:
Lancet (London, England). 389(10069)
Summary Background A recombinant adenovirus type-5 vector-based vaccine expressing the glycoprotein of Ebola Zaire Makona variant showed good safety and immunogenicity in a phase 1 trial of healthy Chinese adults. We aimed to assess the safety and im
Autor:
Steven A. Rosenberg, Constance M. Yuan, Marianna Sabatino, Terry J. Fry, Ling Zhang, Hua Zhang, Crystal L. Mackall, Rimas J. Orentas, Alan S. Wayne, Steven A. Feldman, Maryalice Stetler-Stevenson, James N. Kochenderfer, Dave Stroncek, Cindy Delbrook, Nick Tschernia, Nirali N. Shah, Seth M. Steinberg, Daniel W. Lee, Yongzhi K Cui
Publikováno v:
Lancet (London, England). 385(9967)
Summary Background Chimeric antigen receptor (CAR) modified T cells targeting CD19 have shown activity in case series of patients with acute and chronic lymphocytic leukaemia and B-cell lymphomas, but feasibility, toxicity, and response rates of cons
Autor:
S. Rachel Skinner, Henry C Kitchener, Gary Dubin, Jorge Salmerón, Margaret E. Cruickshank, Frank Struyf, Wim Quint, Dominique Descamps, Myron J. Levin, Eduardo Lazcano-Ponce, René H.M. Verheijen, Daniel da Silva, Céline Bouchard, Swee Chong Quek, Karin Hardt, Anne Szarewski, Kah Leng Fong, Arunachalam Ilancheran, Barbara Romanowski, Jack T. Stapleton, Dorothée Meric, M. Rowena Del Rosario-Raymundo, Brecht Geeraerts, Deborah Money, Mark G. Martens, Archana Chatterjee, Marie Pierre David, Suzanne M. Garland
Publikováno v:
Lancet (London, England). 384(9961)
Although adolescent girls are the main population for prophylactic human papillomavirus (HPV) vaccines, adult women who remain at risk of cervical cancer can also be vaccinated. We report data from the interim analysis of the ongoing VIVIANE study, t
Autor:
Chung-Ming Chu, K I Law, Leo L.M. Poon, Kwok-ning Chan, T Y W Hon, J S C Ng, Wing-Chun Ng, Ivan Hung, V. C. C. Cheng, Bo-Jian Zheng, Kin Sang Chan, Kwok-Yung Yuen, Raymond Lai, Yi Guan, Joseph S. M. Peiris, Bone S.F. Tang, CS Chan
Publikováno v:
Lancet (London, England)
The Lancet
The Lancet
Summary Background We investigated the temporal progression of the clinical, radiological, and virological changes in a community outbreak of severe acute respiratory syndrome (SARS). Methods We followed up 75 patients for 3 weeks managed with a stan
Autor:
Lee-Jah, Chang, Kimberly A, Dowd, Floreliz H, Mendoza, Jamie G, Saunders, Sandra, Sitar, Sarah H, Plummer, Galina, Yamshchikov, Uzma N, Sarwar, Zonghui, Hu, Mary E, Enama, Robert T, Bailer, Richard A, Koup, Richard M, Schwartz, Wataru, Akahata, Gary J, Nabel, John R, Mascola, Theodore C, Pierson, Barney S, Graham, Julie E, Ledgerwood, Phyllis, Renehan
Publikováno v:
Lancet (London, England). 384(9959)
Chikungunya virus--a mosquito-borne alphavirus--is endemic in Africa and south and southeast Asia and has recently emerged in the Caribbean. No drugs or vaccines are available for treatment or prevention. We aimed to assess the safety, tolerability,
Autor:
Oliver Lenz, Patrick Marcellin, Fred Poordad, Guy De La Rosa, Sivi Ouwerkerk-Mahadevan, Yves Horsmans, Ewa Janczewska, Michael Manns, M. Beumont-Mauviel, Federico Guillermo Villamil, Jane Scott, Evaldo Stanislau Affonso de Araújo, Rekha Sinha, R. Kalmeijer, Maria Buti, Monika Peeters
Publikováno v:
Lancet (London, England). 384(9941)
Pegylated interferon (peginterferon) alfa 2a or 2b plus ribavirin regimens were the standard of care in patients with hepatitis C virus (HCV) infection, but the sustained virological response can be suboptimum in patients with HCV genotype 1 infectio
Autor:
Felicetto Ferrara, Charles A Schiffer
Publikováno v:
Lancet (London, England). 381(9865)
The outlook for patients with acute myeloid leukaemia has improved in the past 30 years. Unlike other cancers, much of this progress is attributable to refinement of supportive treatment, rather than the introduction of new drugs. New antibacterial a
Autor:
David C. Wheeler, Natasha Old, Suzanne Luck, Colette Smith, Anna Stanton, Paul Sweny, Ruth Kinyanjui, Gareth Jones, Steven Prideaux, Elizabeth Woodford, Mohamed Osman, Sylvie Pichon, Andrew K. Burroughs, Erin McCarrell, James O'Beirne, Sowsan Atabani, Marisa Lanzman, Paul D. Griffiths, M Harber, Douglas Thorburn, Emily Rothwell, David Patch, Claire Atkinson, Richard S. B. Milne, Tanzina Haque, Vincent C. Emery, Andrew Davenport
Publikováno v:
Lancet (London, England). 377(9773)
SummaryBackgroundCytomegalovirus end-organ disease can be prevented by giving ganciclovir when viraemia is detected in allograft recipients. Values of viral load correlate with development of end-organ disease and are moderated by pre-existing natura
Autor:
Otfried Kistner, Sandor Fritsch, Hartmut J. Ehrlich, P. Noel Barrett, Gerald Aichinger, Mary Kate Hart, Wael El-Amin, Gregory Berezuk
Publikováno v:
Lancet (London, England). 377(9767)
Summary Background The use of cell-culture technologies for the manufacture of influenza vaccines might contribute to improved strain selection and robust vaccine supplies. We investigated the safety, immunogenicity, and protective efficacy of a Vero
Autor:
Sasha C. Appleton, Mercedes C. Becerra, Megan Murray, Jaime Bayona, Katiuska Chalco, Molly F. Franke, Carole D. Mitnick, Fernando Arteaga, Sidney Atwood
Publikováno v:
Lancet (London, England). 377(9760)
Summary Background Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis have emerged as major global health threats. WHO recommends contact investigation in close contacts of patients with MDR and XDR tuberculosis. We aimed to