Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Masanobu Kitagawa"'
Autor:
Morito Kurata, Sachiko Ishibashi, Sayuri Shiono, Towako Taguchi, Iichiroh Onishi, Yuko Kinowaki, Masahide Yamamoto, Kouhei Yamamoto, Yunosuke Sato, Masumi Ikeda, Masanobu Kitagawa
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 101(2)
The overexpression of glutathione peroxidase 4 (GPX4; an enzyme that suppresses peroxidation of membrane phospholipids) is considered a poor prognostic predictor of diffuse large B-cell lymphoma (DLBCL). However, the mechanisms employed in GPX4 overe
Fatty acid beta oxidation enzyme HADHA is a novel potential therapeutic target in malignant lymphoma
Autor:
Yuuki Aizawa, Jun Hashimoto, Morito Kurata, Shinya Abe, Masahide Yamamoto, Taro Takemura, Sachiko Ishibashi, Kouhei Yamamoto, Masanobu Kitagawa, Nobutaka Hanagata, Osamu Miura, Ayaka Honda
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 100(3)
Cancer cells, including malignant lymphoma cells, alter their metabolism, termed “metabolic reprograming,” on initiation of malignant transformation as well as upon accumulation of genetic abnormalities. Here, to identify a novel therapeutic targ
Autor:
Masanobu Kitagawa, Kouhei Yamamoto, Anna Tatsuzawa, Masumi Ikeda, Masahide Yamamoto, Sachiko Ishibashi, Morito Kurata, Osamu Miura, Yuko Kinowaki
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 98(5)
Regulation of oxidative stress and redox systems has important roles in carcinogenesis and cancer progression, and for this reason has attracted much attention as a new area of cancer therapeutic targets. Glutathione peroxidase 4 (GPX4), an antioxida