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Autor:
Dirk J. Duncker, Evangelos P. Daskalopoulos, Daphne P.M. de Wijs-Meijler, Irwin K.M. Reiss, Daphne Merkus, Kevin C.M. Hermans, André Uitterdijk, W. Matthijs Blankesteijn
Publikováno v:
Laboratory Investigation, 96(2), 168-176. Nature Publishing Group
Modulation of Wnt/Frizzled signaling with UM206 reduced infarct expansion and prevented heart failure development in mice, an effect that was accompanied by increased myofibroblast presence in the infarct, suggesting that Wnt/Frizzled signaling has a