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Autor:
Bruce Spinowitz, Ritesh Raichoudhury
Publikováno v:
Kidney Int Suppl (2011)
The management of anemia of chronic kidney disease (CKD) is often challenging. In particular, for patients with underlying inflammation, comorbid type 2 diabetes or cancer, those hospitalized, and recipients of a kidney transplant, the management of
Autor:
Joseph V. Bonventre
Publikováno v:
Kidney International Supplements
Tubular injury has a major etiological role in fibrosis. For many years, this relationship has been dominated by the perception that epithelial cells are transformed into myofibroblasts that proliferate and generate fibrotic matrix-the so-called epit
Publikováno v:
Kidney International Supplements
There is a close spatial and temporal relationship between macrophage accumulation and active renal fibrosis in human and experimental kidney disease. Different subtypes of macrophages have been identified. Pro-inflammatory M1-type macrophages can ca
Autor:
Kumar Sharma
Publikováno v:
Kidney International Supplements
Obesity in combination with diabetes and hypertension likely is contributing to the increasing incidence of chronic kidney disease (CKD) in the 21st century worldwide and requires novel insights and strategies for treatment. There is an increasing re
Publikováno v:
Kidney International Supplements
Patients with terminal cardiac or renal disease have few therapeutic options besides organ transplantation. Optimally, cell therapies would be used both in acute and chronic stages of such diseases. In the injured myocardium, the main therapeutic goa
Publikováno v:
Kidney International Supplements
Surveillance biopsies have contributed to the understanding of the natural history of renal allograft lesions. Subclinical rejection, defined as the presence of histological lesions, indistinguishable from acute rejection in stable grafts, is associa
Autor:
Yoshiharu Tsubakihara, Hiroyasu Yamamoto, Takayuki Hamano, Naohiko Fujii, Terumasa Hayashi, Kunitoshi Iseki
Publikováno v:
Kidney International Supplements
Reportedly, serum ferritin levels are much lower in Japanese hemodialysis (HD) patients than their Western counterparts. Therefore, the cutoff values of ferritin and transferrin saturation (TSAT) for iron deficiency might differ from other countries.