Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hitoshi Endou"'
Autor:
Daisaku Miura, Yoshikatsu Kanai, Rie Noshiro, Ho Jung Shin, Tomohiro Terada, Hiroki Miyazaki, Naohiko Anzai, Hitoshi Endou, Ken-ichi Inui, Xin He, Takeshi Sakata
Publikováno v:
Kidney International. 70(2):275-282
The proton-coupled peptide transporter PEPT2 ( SLC15A2 ) mediates the high-affinity low-capacity transport of small peptides as well as various oral peptide-like drugs in the kidney. In contrast to its well-characterized transport properties, there i
Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction
Publikováno v:
Kidney International. 68(6):2704-2713
Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction. Background Bilateral ureteral obstruction (BUO) is characterized by the development of hemodynamic and tubular lesions. However, little is known abo
Autor:
Eiji Higashihara, Fumio Bessho, Yukino Nishibori, Jamshid Khoshnoodi, L.I. Liu, Makoto Hosoyamada, Shori Takahashi, Karl Tryggvason, Hitoshi Takenaka, Vesa Ruotsalainen, Hitoshi Endou, David B. Kershaw, Akihiko Kudo, Kunimasa Yan
Publikováno v:
Kidney International. 66:1755-1765
Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. Background Podocin is a membrane-integrated protein that is located at the glomerular slit diaphragm and directly interacts with nephrin. The ge
Autor:
Hitoshi Endou, Yasunori Utsunomiya, Michio Takeda, Kimiyoshi Ichida, Tatsuo Hosoya, Hiroaki Kimura, Makoto Hosoyamada
Publikováno v:
Kidney International. 63:143-155
Urate transport via human PAH transporter hOAT1 and its gene structure.BackgroundWe recently cloned the human organic anion transporter 1 (hOAT1) as a p-aminohippurate (PAH) transporter. Whether urate is transported by the PAH transporter in humans r
Autor:
Akihiro Tojo, Takashi Sekine, Yoshikatsu Kanai, Hitoshi Endou, Makoto Hosoyamada, Michio Takeda
Publikováno v:
Kidney International. 56:2128-2136
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. Background Cephaloridine (CER) has been used to elucidate the mechanisms of cephalosporin antibiotic-induced nephrotoxicity. Organic anion transporters have bee
Autor:
Masaaki Fujimura, Koichiro Akakura, Yasuhiro Shigeta, Nesar Ahmed, Arthit Chairoungdua, Kenichi Mizoguchi, Do Kyung Kim, Hirotaka Matsuo, Yoshikatsu Kanai, Shinichi Sakamoto, Takuya Ueda, Naohiko Anzai, Tomohiko Ichikawa, Hiroshi Ito, Hitoshi Endou
Publikováno v:
Kidney international. 69(7)
Cystinuria is caused by the inherited defect of apical membrane transport systems for cystine and dibasic amino acids in renal proximal tubules. Mutations in either SLC7A9 or SLC3A1 gene result in cystinuria. The mutations of SLC7A9 gene have been id
Publikováno v:
Kidney international. 66(3)
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese. Background Recently, SLC22A12 has been identified as a urate-anion exchanger in the human kidney. Methods We screened for polymorphisms of SLC22A12 and conducted an asso
Autor:
Yuichi Sugiyama, Akira Takadate, Hitoshi Endou, Hiroyuki Kusuhara, Tsuneo Deguchi, Masaki Otagiri
Publikováno v:
Kidney international. 65(1)
Characterization of uremic toxin transport by organic anion transporters in the kidney. Background Harmful uremic toxins, such as indoxyl sulfate (IS), 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), indoleacetate (IA), and hippurate (HA), accu
Autor:
Makoto Hosoyamada, Yoshikatsu Kanai, Hitoshi Endou, Noriko Nakajima, Takashi Sekine, Seok Ho Cha, Akihiro Tojo, Kunimasa Yan, Shouichi Awa
Publikováno v:
Kidney international. 57(4)
Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney. Background The cDNA of the multispecific organic anion transporter 1 (OAT1) responsible for the tubular secretion of organic anions was recently isolated
Publikováno v:
Kidney international. 41(1)
Cisplatin-induced alterations in renal structure, ammoniagenesis, and gluconeogenesis of rats. Cisplatin [cis-diamminedichloroplatinum (II): CDDP] is a widely used cancer chemotherapeutic agent which has been shown to cause dose-related acute renal f