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Autor:
Shih-Hua Lin, Gabrielle G. Gilmer, Lihe Chen, Kavee Limbutara, Hyun Jun Jung, Chung-Lin Chou, Sookkasem Khositseth, Mark A. Knepper, Chin-Rang Yang, Chih-Chien Sung
Publikováno v:
Kidney Int
Lithium salts, used for treating bipolar disorder, frequently induce nephrogenic diabetes insipidus (NDI) thereby limiting therapeutic success. NDI is associated with loss of expression of the gene coding for the molecular water channel, aquaporin-2,
Autor:
Ulf Nyman, Hans Pottel, Jonas Björk, Ulla B. Berg, Laurence Dubourg, Arend Bökenkamp, Karin Littmann, Ian Jones, Per Sjöström, Magnus Hansson, Kajsa Åsling-Monemi, Luciano Selistre, Pierre Delanaye
Publikováno v:
Pottel, H, Björk, J, Bökenkamp, A, Berg, U, Åsling-Monemi, K, Selistre, L, Dubourg, L, Hansson, M, Littmann, K, Jones, I, Sjöström, P, Nyman, U & Delanaye, P 2019, ' Estimating glomerular filtration rate at the transition from pediatric to adult care ', Kidney International, vol. 95, no. 5, pp. 1234-1243 . https://doi.org/10.1016/j.kint.2018.12.020
Kidney International, 95(5), 1234-1243. Nature Publishing Group
Kidney International, 95(5), 1234-1243. Nature Publishing Group
The current Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend the use of the bedside creatinine-based Chronic Kidney Disease in Children (CKiD) equation to estimate glomerular filtration rate (GFR) in children and the Chronic Kidn
Publikováno v:
Kidney International. 90:67-76
Tissue preconditioning, whereby various short term stressors initiate organ resistance to subsequent injury, is well recognized. However, clinical preconditioning of the kidney for protection against acute kidney injury (AKI) has not been established
Publikováno v:
Kidney International. 89:1324-1330
The kidney is influenced by circadian rhythms and is entrained to the sleep-wake cycle allowing anticipation of the metabolic and physiological demands of the kidney throughout a 24-hour cycle. Although sleep disruption has been studied extensively i
Autor:
El Hassane Trabelssi, Benyounes Ramdani, Marc E. De Broe, Naïma Benahadi, Rabia Bayahia, Monique Elseviers, Mohamed Zamd, Mohammed Benghanem Gharbi, Abdelali Belghiti Alaoui
Publikováno v:
Kidney international
The prevalence of hypertension, diabetes, obesity, and chronic kidney disease (CKD) in an adult Arabic-Berber population was investigated according to 2012 KDIGO guidelines. A stratified, randomized, representative sample of 10,524 participants was o
Autor:
Jonathan R. Manning, David J. Webb, Carolynn Cairns, Jane Goddard, Jackie F. Price, Douglas J. Lamont, Stela McLachlan, Mark W. J. Strachan, John J. Mullins, Boris Betz, Sara J. Jenks, Bryan R. Conway, Andrew D. Cronshaw, Jeremy Hughes
Publikováno v:
Betz, B B, Jenks, S J, Cronshaw, A D, Lamont, D J, Cairns, C, Manning, J R, Goddard, J, Webb, D J, Mullins, J J, Hughes, J, McLachlan, S, Strachan, M W J, Price, J F & Conway, B R 2016, ' Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes ', Kidney International, vol. 89, no. 5, pp. 1125–1135 . https://doi.org/10.1016/j.kint.2016.01.015
Many diabetic patients suffer from declining renal function without developing albuminuria. To identify alternative biomarkers for diabetic nephropathy (DN) we performed urinary peptidomic analysis in a rodent model in which hyperglycemia and hyperte
Autor:
Richard B. Kim, Bridget L. Morse, Ognjenka Djurdjev, Mila Tang, Norman Muirhead, Brendan Barrett, Daniel T. Holmes, Francois Madore, Catherine M. Clase, Claudio Rigatto, Adeera Levin, Mohsen Agharazii, Joanne Blouin, France Samson, Ayub Akbarii, Judy Cheesman, Jennilea Courtney, Sabrina Hamer, Edita Delic, Valerie Cronin, Paul Barré, Jeffrey Golden, Elizabeth Langille, Sandra Adams, Janet Morgan, Catherine Clase, Cathy Moreau, Susan Cooper, Brian Forzley, Susan Caron, Shauna Granger, Susan Valley, Helen Sather, Serge Cournoyer, Lorraine Menard, Michèle Roy, Hélène Skidmore, Dolores Beaudry, Janis Dionne, Josephine Chow, Valla Sahraei, Sandra Donnelly, Niki Dacouris, Rosa Marticorena, Brenda Hemmelgarn, Sharon Gulewich, Troy Hamilton, Paul Keown, Nadia Zalunardo, Daniel Rogers, Reena Tut, Matthew Paquette, Rossitta Yung, Nancy Ferguson, Helen Chiu, Kathleen Carlson, Lina Sioson, Taylor Perry, Zainab Sheriff, Naama Rozen, Charmaine Lok, Michelle Cross, Cathy Forrester, Alexandra Cotoi, François Madore, Manon Maltais, Louise Moist, Kerri Gallo, Sarah Langford, Leah Slamen, Danielle Cram, Mary Jeanne Edgar, Taylor Gray, Cameron Edgar, Karen Groeneweg, Eileen McKinnon, Erin McRae, Kyla Blackie, Bharat Nathoo, Kimmy Lau, Malvinder Parmar, Sylvie Gelinas, Martine Leblanc, Lucie Lépine, Dolores Friesen, Steven Soroka, Susan Fleet, Jeanette Squires, Siva Thanamayooran, Michael Binder, Christine Hines, Brenda McNeil, Patrice McDougall, Joy Howard, Deborah Gillis, Kathleen Hines, Sheldon Tobe, Mary Chessman, Nancy Perkins, Martha Agelopoulos, Stacey Knox, Tiffany Richards, Marcello Tonelli, Susan Szigety, Dawn Opgenorth, Karen Yeates, Karen Mahoney
Publikováno v:
Paediatrics Publications
Cardiovascular disease is more common in patients with chronic kidney disease (CKD), and traditional risk factors do not adequately predict those at risk for cardiovascular (CV) events. Recent evidence suggests elevated trimethylamine N-oxide (TMAO),
Publikováno v:
Kidney International. 89:886-896
Available experimental evidence suggests a role for high-density lipoprotein cholesterol (HDL-C) in incident chronic kidney disease (CKD) and its progression. However, clinical studies are inconsistent. We therefore built a cohort of 1,943,682 male U
Autor:
Dickson W. L. Wong, Wai Han Yiu, Kar Neng Lai, Loretta Y.Y. Chan, Hui Y. Lan, Irene Yam, Rui Xi Li, Joseph Leung, Sydney C.W. Tang, Haojia Wu
Publikováno v:
Kidney International. 89:386-398
Kallistatin is a serine protease inhibitor with anti-inflammatory, anti-angiogenic, and anti-oxidative properties. Since oxidative stress plays a critical role in the pathogenesis of diabetic nephropathy, we studied the effect and mechanisms of actio
Autor:
William C. Knowler, Robert G. Nelson, Andrzej S. Krolewski, Monika A. Niewczas, Gudeta D. Fufaa, Meda E. Pavkov, E. Jennifer Weil, Kevin V. Lemley
Publikováno v:
Kidney international
Elevated serum tumor necrosis factor receptor 1 (TNFR1) and 2 (TNFR2) concentrations are strongly associated with increased risk of end-stage renal disease in type 2 diabetes. However, little is known about the early glomerular structural lesions tha