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Autor:
Peter J. Nelson, Matthias Kretzler, Marie C. Hogan, Daniel C. Cattran, Jonathan P. Troost, Heather N. Reich, Debbie S. Gipson, John C. Lieske, Sharon G. Adler, Gerald B. Appel
Publikováno v:
Kidney International. 90:1080-1089
Random urine protein creatinine ratios are used to estimate 24-hour urine protein excretion, which is considered a diagnostic gold standard. However, few studies are available of the sensitivity and specificity of this estimation in patients with glo
Publikováno v:
Kidney international. 92(4)
Autor:
Kousuke Negishi, Eisei Noiri, Takehiro Matsubara, Kent Doi, Sho Hasegawa, Takeshi Ishii, Toshiro Fujita, Naoki Yahagi, Takeshi Sugaya, Yoshifumi Hamasaki, Daisuke Katagiri
Publikováno v:
Kidney International. 82(10):1114-1120
Prerenal acute kidney injury (AKI) is thought to be a reversible loss of renal function without structural damage. Although prerenal and intrinsic AKI frequently coexist in clinical situations, serum creatinine and urine output provide no information
Autor:
Chi-yuan Hsu, Dawei Xie, Sushrut S. Waikar, Joseph V. Bonventre, Xiaoming Zhang, Venkata Sabbisetti, Theodore E. Mifflin, Josef Coresh, Clarissa J. Diamantidis, Jiang He, Claudia M. Lora, Edgar R. Miller, Robert G. Nelson, Akinlolu O. Ojo, Mahboob Rahman, Jeffrey R. Schelling, Francis P. Wilson, Paul L. Kimmel, Harold I. Feldman, Ramachandran S. Vasan, Kathleen D. Liu, Lawrence J. Appel, Alan S. Go, John W. Kusek, James P. Lash, Akinlolu Ojo, Raymond R. Townsend
Publikováno v:
Kidney international. 91(1)
Few investigations have evaluated the incremental usefulness of tubular injury biomarkers for improved prediction of chronic kidney disease (CKD) progression. As such, we measured urinary kidney injury molecule-1, neutrophil gelatinase–associated l
Autor:
Prasad Devarajan, Takeshi Sugaya, Eisei Noiri, I. Kundi, Catherine L. Dent, Page C. Moore, Didier Portilla, Kiran K. Nagothu
Publikováno v:
Kidney International. 73:465-472
Acute kidney injury (AKI) is a major complication of cardiac bypass surgery. We examined whether levels of liver fatty acid-binding protein (L-FABP) can be an early biomarker for ischemic injury by measuring this protein in the urine of 40 pediatric
Autor:
Brad H. Rovin, Daniel J. Birmingham, Chack-Yung Yu, Lee A. Hebert, Haikady N. Nagaraja, Ganesh Shidham, Michael G Bissell, X. Zou
Publikováno v:
Kidney International. 72:865-870
The diagnosis of glomerulonephritis flares in systemic lupus erythematosus (SLE) is usually based on whether the magnitude of proteinuria has changed. Our study tests two methods to assess proteinuric change: protein/creatinine (P/C) ratios of intend
Publikováno v:
Kidney International. 71(11):1181-1184
CASE PRESENTATION A 49-year-old man was referred for evaluation of rising plasma creatinine. The patient had undergone a partial gastrectomy 4 years previously, for resection of a gastrointestinal stromal tumor. He was diagnosed with recurrent diseas
Autor:
Shih-Jen Hwang, Nader Rifai, Joanne M. Murabito, Ramachandran S. Vasan, Martin G. Larson, James B. Meigs, Emelia J. Benjamin, Eric P. Leip, Daniel Levy, Caroline S. Fox
Publikováno v:
Kidney International. 69:2064-2069
Experimental models suggest that increased aldosterone and sodium intake are associated with renovascular damage and resultant proteinuria. We hypothesized that serum aldosterone and urinary sodium would be associated with urinary albumin excretion,
Publikováno v:
Kidney International. 69(6):1041-1047
The treatment of cystinuria is hampered by methods used to measure urinary lithogenicity. Most cystine assays cannot reliably distinguish cystine from soluble thiol drug–cysteine complexes. We used a solid-phase assay of urinary cystine capacity in
Publikováno v:
Kidney International. 66:2374-2381
Predictive value of urinary micro-cholesterol (mCHO) levels in patients with progressive glomerular disease. Background Trace amounts of lipids are present in the urine of patients with glomerular disease, raising the possibility that the excess lipi