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Autor:
M. Arfan Ikram, Jie Ding, Vilmundur Gudnason, Sanaz Sedaghat, Andrew S. Levey, Osorio Meirelles, Lenore J. Launer, Sigurdur Sigurdsson, Mark A. van Buchem, Gudny Eiriksdottir
Publikováno v:
Kidney International, 94(3), 608-615. Elsevier Inc.
Kidney International, 94(3), 608-615
Kidney International, 94(3), 608-615
Decreased glomerular filtration rate (GFR) and albuminuria may be accompanied by brain pathology. Here we investigated whether changes in these kidney measures are linked to development of new MRI-detected infarcts and microbleeds, and progression of
Autor:
Dimitris Rizopoulos, Sharda S. Anroedh, Olivier C. Manintveld, Isabella Kardys, Kadir Caliskan, Victor A. Umans, Hans L. Hillege, Jan H. Cornel, Alina A. Constantinescu, Milos Brankovic, Nick van Boven, K. Martijn Akkerhuis, Eric Boersma, Sara J. Baart
Publikováno v:
Kidney International, 93(4), 952-960. ELSEVIER SCIENCE INC
Kidney International, 93(4), 952-960. Elsevier Inc.
Kidney International, 93(4), 952-960. Elsevier Inc.
Renal dysfunction is an important component of chronic heart failure (CHF), but its single assessment does not sufficiently reflect clinically silent progression of CHF prior to adverse clinical outcome. Therefore, we aimed to investigate temporal ev
Autor:
Jonathan R. Manning, David J. Webb, Carolynn Cairns, Jane Goddard, Jackie F. Price, Douglas J. Lamont, Stela McLachlan, Mark W. J. Strachan, John J. Mullins, Boris Betz, Sara J. Jenks, Bryan R. Conway, Andrew D. Cronshaw, Jeremy Hughes
Publikováno v:
Betz, B B, Jenks, S J, Cronshaw, A D, Lamont, D J, Cairns, C, Manning, J R, Goddard, J, Webb, D J, Mullins, J J, Hughes, J, McLachlan, S, Strachan, M W J, Price, J F & Conway, B R 2016, ' Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes ', Kidney International, vol. 89, no. 5, pp. 1125–1135 . https://doi.org/10.1016/j.kint.2016.01.015
Many diabetic patients suffer from declining renal function without developing albuminuria. To identify alternative biomarkers for diabetic nephropathy (DN) we performed urinary peptidomic analysis in a rodent model in which hyperglycemia and hyperte
Autor:
Kousuke Negishi, Eisei Noiri, Takehiro Matsubara, Kent Doi, Sho Hasegawa, Takeshi Ishii, Toshiro Fujita, Naoki Yahagi, Takeshi Sugaya, Yoshifumi Hamasaki, Daisuke Katagiri
Publikováno v:
Kidney International. 82(10):1114-1120
Prerenal acute kidney injury (AKI) is thought to be a reversible loss of renal function without structural damage. Although prerenal and intrinsic AKI frequently coexist in clinical situations, serum creatinine and urine output provide no information
Autor:
Chi-yuan Hsu, Dawei Xie, Sushrut S. Waikar, Joseph V. Bonventre, Xiaoming Zhang, Venkata Sabbisetti, Theodore E. Mifflin, Josef Coresh, Clarissa J. Diamantidis, Jiang He, Claudia M. Lora, Edgar R. Miller, Robert G. Nelson, Akinlolu O. Ojo, Mahboob Rahman, Jeffrey R. Schelling, Francis P. Wilson, Paul L. Kimmel, Harold I. Feldman, Ramachandran S. Vasan, Kathleen D. Liu, Lawrence J. Appel, Alan S. Go, John W. Kusek, James P. Lash, Akinlolu Ojo, Raymond R. Townsend
Publikováno v:
Kidney international. 91(1)
Few investigations have evaluated the incremental usefulness of tubular injury biomarkers for improved prediction of chronic kidney disease (CKD) progression. As such, we measured urinary kidney injury molecule-1, neutrophil gelatinase–associated l
Publikováno v:
Kidney International. 79:89-98
Delayed graft function (DGF), especially long-lasting DGF, complicates kidney transplant outcome. Neutrophil gelatinase-associated lipocalin (NGAL) is an acute kidney injury marker; therefore, we tested whether urine NGAL could predict DGF, prolonged
Autor:
Eric Schiffer, Torsten Kirsch, Harald Mischak, Marion Haubitz, Korbinian Brand, Stefan Herget-Rosenthal, Eva M. Weissinger, Jochen Metzger, Ebru Mentes, Perihan Ulger
Publikováno v:
Kidney International; Vol 78
Early and accurate detection of acute kidney injury (AKI) is needed to prevent the progression to chronic kidney disease and to improve outcome. Here we used capillary electrophoresis-mass spectrometry to identify urinary peptides predictive of AKI i
Autor:
Anthony W. C. Tang, Sunny Sze Ho Wong, Joseph Leung, Yiu Wing Ho, Kar Neng Lai, Sydney C.W. Tang
Publikováno v:
Kidney International. 77(6):543-549
Since the efficacy of mycophenolate mofetil (MMF) to treat immunoglobulin A (IgA) nephropathy is controversial, we extended our original study by following 40 Chinese patients with established IgA nephropathy for 6 years. All patients were maintained
Autor:
Michael E. Matheny, Colin M. Sox, Catherine Yoon, Balthasar L. Hug, Daniel J. Witkowski, David W. Bates, Diane L. Seger, Carol A. Keohane
Publikováno v:
Kidney International. 76(11):1192-1198
Medication errors in patients with reduced creatinine clearance are harmful and costly; however, most studies have been conducted in large academic hospitals. As there are few studies regarding this issue in smaller community hospitals, we conducted
Autor:
Andrew D. Rule, Gary L. Schwartz, L. Joseph Melton, Sundeep Khosla, Kent R. Bailey, John C. Lieske
Publikováno v:
Kidney International. 75(10):1071-1078
Estimation of creatinine clearance requires knowledge of creatinine generation which can vary in different groups of patients. Since the main source of creatinine is muscle we used dual-energy X-ray absorptiometry to measure the mass of muscle in a c