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Autor:
M. Arfan Ikram, Jie Ding, Vilmundur Gudnason, Sanaz Sedaghat, Andrew S. Levey, Osorio Meirelles, Lenore J. Launer, Sigurdur Sigurdsson, Mark A. van Buchem, Gudny Eiriksdottir
Publikováno v:
Kidney International, 94(3), 608-615. Elsevier Inc.
Kidney International, 94(3), 608-615
Kidney International, 94(3), 608-615
Decreased glomerular filtration rate (GFR) and albuminuria may be accompanied by brain pathology. Here we investigated whether changes in these kidney measures are linked to development of new MRI-detected infarcts and microbleeds, and progression of
Autor:
Gang Xu, Shuwang Ge, Kun Wang, Ying Yao, Ran Luo, Junhua Li, Meng Zhang, Lei Dong, Zhixiang Wang, Yichun Cheng
Publikováno v:
Kidney International
Kidney international, In Press
Kidney international, In Press
In December 2019, a coronavirus 2019 (COVID-19) disease outbreak occurred in Wuhan, Hubei Province, China, and rapidly spread to other areas worldwide. Although diffuse alveolar damage and acute respiratory failure were the main features, the involve
Autor:
Chengxiang Qiu, Gudeta D. Fufaa, Caroline Gluck, Yong Chen, Sayuko Kobes, Dominic S. Raj, Katalin Susztak, William C. Knowler, Jing Huang, Robert L. Hanson, Robert G. Nelson
Publikováno v:
Kidney International. 93:1417-1431
Diabetic nephropathy accounts for most of the excess mortality in individuals with diabetes, but the molecular mechanisms by which nephropathy develops are largely unknown. Here we tested cytosine methylation levels at 397,063 genomic CpG sites for a
Autor:
Matthias Stuber, Bastien Milani, Michel Burnier, Bruno Vogt, Edward Pivin, Agata Podhajska, Menno Pruijm
Publikováno v:
Kidney international, vol. 93, no. 4, pp. 932-940
Kidney Int
Kidney Int
Renal tissue hypoxia is a final pathway in the development and progression of chronic kidney disease (CKD), but whether renal oxygenation predicts renal function decline in humans has not been proven. Therefore, we performed a prospective study and m
Autor:
Dimitris Rizopoulos, Sharda S. Anroedh, Olivier C. Manintveld, Isabella Kardys, Kadir Caliskan, Victor A. Umans, Hans L. Hillege, Jan H. Cornel, Alina A. Constantinescu, Milos Brankovic, Nick van Boven, K. Martijn Akkerhuis, Eric Boersma, Sara J. Baart
Publikováno v:
Kidney International, 93(4), 952-960. ELSEVIER SCIENCE INC
Kidney International, 93(4), 952-960. Elsevier Inc.
Kidney International, 93(4), 952-960. Elsevier Inc.
Renal dysfunction is an important component of chronic heart failure (CHF), but its single assessment does not sufficiently reflect clinically silent progression of CHF prior to adverse clinical outcome. Therefore, we aimed to investigate temporal ev
Autor:
Bettina Zelger, Andreas Pascher, Stefan Schneeberger, H. G. Schwelberger, Robert Öllinger, Katja Kotsch, Johann Pratschke, Paul Viktor Ritschl, Hubert Hackl, Diana Stauch, Gerald Brandacher, Arne Sattler, Julia Günther, Matthias Biebl, Thomas Resch, Susanne Ebner
Publikováno v:
Kidney International. 91:1447-1463
The definition of biological donor organ age rather than chronological age seems obvious for the establishment of a valid pre-transplant risk assessment. Therefore, we studied gene expression for candidate markers in 60 zero-hour kidney biopsies. Com
Autor:
Johannes F.E. Mann, Sheldon W. Tobe, Roland E. Schmieder, Joshua I. Barzilay, Catherine M. Clase, Peggy Gao, Salim Yusuf, Koon K. Teo, Andrew Smyth
Publikováno v:
Kidney International. 91:683-690
Initiation of blockade of the renin-angiotensin system may cause an acute decrease in glomerular filtration rate (GFR): the prognostic significance of this is unknown. We did a post hoc analysis of patients with, or at risk for, vascular disease, in
Publikováno v:
Kidney International. 89:1324-1330
The kidney is influenced by circadian rhythms and is entrained to the sleep-wake cycle allowing anticipation of the metabolic and physiological demands of the kidney throughout a 24-hour cycle. Although sleep disruption has been studied extensively i
Autor:
El Hassane Trabelssi, Benyounes Ramdani, Marc E. De Broe, Naïma Benahadi, Rabia Bayahia, Monique Elseviers, Mohamed Zamd, Mohammed Benghanem Gharbi, Abdelali Belghiti Alaoui
Publikováno v:
Kidney international
The prevalence of hypertension, diabetes, obesity, and chronic kidney disease (CKD) in an adult Arabic-Berber population was investigated according to 2012 KDIGO guidelines. A stratified, randomized, representative sample of 10,524 participants was o
Autor:
Jonathan R. Manning, David J. Webb, Carolynn Cairns, Jane Goddard, Jackie F. Price, Douglas J. Lamont, Stela McLachlan, Mark W. J. Strachan, John J. Mullins, Boris Betz, Sara J. Jenks, Bryan R. Conway, Andrew D. Cronshaw, Jeremy Hughes
Publikováno v:
Betz, B B, Jenks, S J, Cronshaw, A D, Lamont, D J, Cairns, C, Manning, J R, Goddard, J, Webb, D J, Mullins, J J, Hughes, J, McLachlan, S, Strachan, M W J, Price, J F & Conway, B R 2016, ' Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes ', Kidney International, vol. 89, no. 5, pp. 1125–1135 . https://doi.org/10.1016/j.kint.2016.01.015
Many diabetic patients suffer from declining renal function without developing albuminuria. To identify alternative biomarkers for diabetic nephropathy (DN) we performed urinary peptidomic analysis in a rodent model in which hyperglycemia and hyperte