Zobrazeno 71 - 80
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NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy
Autor:
John R. Asplin, Felix Knauf, Rachel J. David, Richard A. Flavell, Ignacio Granja, Insa M. Schmidt, Peter S. Aronson, Gilbert W. Moeckel
Publikováno v:
Kidney international. 84(5)
Oxalate nephropathy with renal failure is caused by multiple disorders leading to hyperoxaluria due to either overproduction of oxalate (primary hyperoxaluria) or excessive absorption of dietary oxalate (enteric hyperoxaluria). To study the etiology
Autor:
John D. Ruby, Nyles W. Charon, Changbin Qiu, György Losonczy, Lennie Samsell, Cheryl Hill, Rocco C. Venuto, Tamás Sütő, Chris Baylis
Publikováno v:
Kidney International. 48(4):1272-1277
Acute changes in urinary excretion of nitrite + nitrate do not necessarily predict renal vascular NO production. NO 2 + NO 3 (NO x ), the stable oxidation products of NO, and cGMP are widely accepted as indices of in vivo NO production. Whether acute
Publikováno v:
Kidney International. 48:111-117
PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Deposition of type III collagen protein is increased when cultured rat mesangial cells are cultured in media containing high glucose concen
Publikováno v:
Kidney International. 47(6):1615-1623
Modulation of salt transport rate affects DNA synthesis in vivo in rat renal tubules. In adult male Wistar rats we investigated whether cell proliferation contributes to salt load-induced hypertrophy of distal tubules. In one treatment group salt tra
Autor:
David A. Bushinsky
Publikováno v:
Kidney International. 47(6):1816-1832
A 5-year-old boy was admitted to the hospital 19 years ago for repair of primary hypospadias. The serum creatinine was 1.2 mg/dl; the BUN, 33 mg/dl; and the bicarbonate concentration, 23 mEq/liter. The creatinine clearance, determined from a 24-hour
Publikováno v:
Kidney International. 47:579-586
Metabolism of low density lipoproteins in nephrotic dyslipidemia: comparison of hypercholesteremia alone and combined hyperlipidemia. High levels of low-density lipoprotein cholesterol (LDL) (hypercholesterolemia) are commonly present in the nephroti
Autor:
Donna Lombardi, Jürgen Floege, Katherine L. Gordon, Bessie A. Young, Pamela Pritzl, Richard J. Johnson, Jeffrey W. Pippin, Charles E. Alpers, William G. Couser, Giulio Gabbiani, Eudora Eng
Publikováno v:
Kidney International. 47:62-69
Modulation of experimental mesangial proliferative nephritis by interferon-γ. The observation that interferon-γ (IFN-γ) inhibits cell proliferation and collagen synthesis of a variety of cell types in culture has suggested that IFN-γ may be usefu
Autor:
Dirk J. Kok, Saeed R. Khan
Publikováno v:
Kidney International. 46(3):847-854
Calcium oxalate nephrolithiasis, a free or fixed particle disease. The chances of stone formation occurring through a free particle mechanism were calculated using the approach of Finlayson and Reid [1]. For these calculations we used new data on nep
Autor:
Z. Reno Vlahcevic, James D. Hanna, William M. Pandak, Douglas M. Heuman, James C.M. Chan, Richard J. Krieg
Publikováno v:
Kidney International. 46:358-364
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7α-hydroxylase in rats with subtotal nephrectomy. Chronic renal failure is associated with hyperlipidemia and atherosclerosis. The mechanism responsib
Autor:
George A. Kaysen, Xihua Sun
Publikováno v:
Kidney International. 45:1381-1387
Albumin and transferrin synthesis are increased in H4 cells by serum from analbuminemic or nephrotic rats. The hepatic synthesis of several proteins, including both albumin and transferrin is increased in the nephrotic syndrome. While active suppress