Zobrazeno 1 - 10
of 92
pro vyhledávání: ''
Autor:
Rudolf P. Wüthrich, Daniel Rodriguez, Yang Liu, Olivier Devuyst, Suhua Zhang, Xueqi Wang, Nilufar Mohebbi, Stephan Segerer, Daniela Spichtig, Sarika Kapoor, Changlin Mei, Hermann Koepsell, Andreas L. Serra
Publikováno v:
Kidney international
Renal tubular epithelial cell proliferation and transepithelial cyst fluid secretion are key features in the progression of polycystic kidney disease (PKD). As the role of the apical renal sodium-glucose cotransporters in these processes is not known
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2013, 83 (4), pp.674-683. ⟨10.1038/ki.2012.478⟩
Kidney International, Nature Publishing Group, 2013, 83 (4), pp.674-683. ⟨10.1038/ki.2012.478⟩
Sodium depletion has a protective effect on target-organ damage in hypertension independent of blood pressure. Here we tested whether chronic dietary sodium restriction may prevent the development of renal alterations associated with insulin resistan
Autor:
Bo Chen, Liliana Viera, David K. Crossman, Angela Brandon, Xinjun Teng, Brett D. Yancey, Molly S. Bray, John A. Thompson, Anupam Agarwal, Stacey S. Kelpke, Kelley M. Bradley, Rakesh P. Patel, Devin E. Eckhoff, Brandon Moore, Phillip Chumley, Hughston Head
Publikováno v:
Kidney international
Renal injury induced by brain death is characterized by ischemia and inflammation, and limiting it is a therapeutic goal that could improve outcomes in kidney transplantation. Brain death resulted in decreased circulating nitrite levels and increased
Autor:
Gexin Zhao, Wei Kong, Mingjiang Xu, Xian Wang, Gerald M. Wilson, Youfei Guan, Cun-Yu Wang, Ming-Ming Zhao, Xiaoyan Dai
Publikováno v:
Kidney international
Vascular calcification is a major risk factor of cardiovascular mortality, particularly for patients with end-stage renal disease and diabetes. Although chronic inflammation is one of the etiologic factors, the underlying mechanism is not fully under
Autor:
Dominique Detaille, Elsa Briones, José M. López-Novoa, Xavier Leverve, Mohamad-Yehia El-Mir, Marta Prieto, Miguel Arévalo, Angel Puente, Ana I. Morales
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2010, 77 (10), pp.861-9. ⟨10.1038/ki.2010.11⟩
Kidney International, Nature Publishing Group, 2010, 77 (10), pp.861-9. ⟨10.1038/ki.2010.11⟩
International audience; The antidiabetic drug metformin can diminish apoptosis induced by oxidative stress in endothelial cells and prevent vascular dysfunction even in nondiabetic patients. Here we tested whether it has a beneficial effect in a rat
Publikováno v:
Kidney International. 75(3):278-284
Hypertonicity in the renal medulla stimulates local cyclooxygenase 2 expression, leading to abundant PGE(2) production. Here we found that mRNA expression by the PGE(2)-activated G-protein-coupled receptors, EP3 and EP4 in the renal medulla was decre
Autor:
Zhibin He, Robert W. Schrier, Y. Yin, Sandor Falk, Sarah Faubel, Jin K. Kim, Iram Zafar, Y. Tao, Charles L. Edelstein
Publikováno v:
Kidney International. 72:1358-1366
Although the receptors for vascular endothelial growth factor (VEGF) exert their effects on vasculogenesis and angiogenesis through receptors located on endothelial cells, recent studies have shown that these receptors are also present on renal tubul
Publikováno v:
Kidney International. 72:1113-1121
Glycation, oxidation, and nitration of endogenous proteins occur spontaneously and these modifications are also present in foods. Increased levels of these chemical changes are associated with chronic renal failure; however, little is known about acu
Autor:
You-Lin Tain, Chris Baylis
Publikováno v:
Kidney International. 72(7):886-889
Dimethylarginine dimethylaminohydrolase (DDAH) metabolizes asymmetric dimethylarginine to generate L-citrulline and is present in large quantities in the kidney. We present a new study that optimizes the Prescott-Jones colorimetric assay to measure D
Autor:
Shuo Quan, David E. Stec, Liming Yang, S. Omura, Rafał Olszanecki, M. Li, Alvin I. Goodman, Nader G. Abraham
Publikováno v:
Kidney International. 72:945-953
Radiocontrast agents are thought to induce acute kidney injury in part through increased production of reactive oxygen species and increased cellular apoptosis. In this study we determined whether heme oxygenase-1 could prevent or reduce radiocontras