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Autor:
Katherine Xu, Krzysztof Kiryluk
Publikováno v:
Kidney International. 101:447-450
Autor:
Koichiro Kato, Keiko Taguchi, Satoru Takahashi, Akihito Otsuki, Masayuki Yamamoto, Ritsuko Shimizu, Akane Yumoto, Yuma Iwamura, Takafumi Suzuki, Masaki Shirakawa, Akira Uruno, Taku Nakai, Mikiko Suzuki, Risa Okada, Daisuke Saigusa, Norio Suzuki, Dai Shiba
Publikováno v:
Kidney International. 101:92-105
Space travel burdens health by imposing considerable environmental stress associated with radioactivity and microgravity. In particular, gravity change predominantly impacts blood pressure and bone homeostasis, both of which are controlled mainly by
Autor:
Benjamin D. Humphreys, Haikuo Li
Publikováno v:
Kidney International. 98:1385-1387
Autor:
Viji Nair, Matthias Kretzler
Publikováno v:
Kidney International. 95:16-18
Publikováno v:
Kidney International. 92:1119-1129
Gene expression differs substantially among individual cells of the same type. We speculate that genes that are expressed in all but a portion of cells of a given cell type would be likely essential and required for either the cell survival (housekee
Autor:
Bettina Zelger, Andreas Pascher, Stefan Schneeberger, H. G. Schwelberger, Robert Öllinger, Katja Kotsch, Johann Pratschke, Paul Viktor Ritschl, Hubert Hackl, Diana Stauch, Gerald Brandacher, Arne Sattler, Julia Günther, Matthias Biebl, Thomas Resch, Susanne Ebner
Publikováno v:
Kidney International. 91:1447-1463
The definition of biological donor organ age rather than chronological age seems obvious for the establishment of a valid pre-transplant risk assessment. Therefore, we studied gene expression for candidate markers in 60 zero-hour kidney biopsies. Com
Autor:
Tally Naveh-Many, Justin Silver
Publikováno v:
Kidney International. 93:7-9
Studies in patients with hypoparathyroidism and knockout mouse models have revealed key transcriptional cascades central for parathyroid organogenesis. Among the transcription factors essential for parathyroid development, Gata3, GCM2, and MafB, are
Autor:
Robert J. Unwin, Robert I. Menzies, Matthew A. Bailey, Amelia R. Howarth, John J. Mullins, Frederick W.K. Tam
Publikováno v:
Kidney International. 88:1079-1087
Chronic activation of the renin-angiotensin system promotes hypertension, renal microvascular dysfunction, tissue hypoxia, and inflammation. Despite similar hypertension, an injurious response to excess angiotensin II is greater in F344 than in Lewis
Autor:
Cuiyan Xin, Naoki Nakagawa, Allie M. Roach, Stuart J. Shankland, Giovanni Ligresti, Natalie Naiman, Suzanne Szak, Ivan G. Gomez, Jeremy S. Duffield, Shuyu Ren
Publikováno v:
Kidney International. 87:1125-1140
MicroRNAs, activated by the enzyme Dicer1, control post-transcriptional gene expression. Dicer1 has important roles in the epithelium during nephrogenesis, but its function in stromal cells during kidney development is unknown. To study this, we inac
Autor:
Rabindra N. Bhattacharjee, Dameng Lian, Aaron Haig, Anthony M. Jevnikar, Yunbo Yang, Zhu-Xu Zhang
Publikováno v:
Kidney International. 87:396-408
Cytokines and chemokines produced by tubular epithelial and infiltrating cells are critical to inflammation in renal ischemia-reperfusion injury. IL-37, a newly described IL-1 family member, inhibits IL-18-dependent pro-inflammatory cytokine producti