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Autor:
Joon Ho Moon, Sang Kyun Sohn, Chul Won Jung, Hyeoung-Joon Kim, Jeffrey H. Lipton, Jiang Cao, Dennis Dong Hwan Kim, Nada Hamad, Qiaoli Zheng
Publikováno v:
Journal of Translational Medicine
Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis pathway might be associated with imatinib response or resistance. Methods This study att
Autor:
Benedict B. Benigno, Noelani Laycock, John F. McDonald, Christopher D. Scharer, Adeboye O. Osunkoya, Sanjay Logani, Carlos S. Moreno
Publikováno v:
Journal of Translational Medicine, Vol 6, Iss 1, p 79 (2008)
Journal of Translational Medicine
Journal of Translational Medicine
BackgroundA large percentage of patients with recurrent ovarian cancer develop resistance to the taxane class of chemotherapeutics. While mechanisms of resistance are being discovered, novel treatment options and a better understanding of disease res