Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Journal of Thermal Biology. 21:365-372
1. 1. We examined rodent cells transfected with an expression plasmid encoding a human small heat shock protein for possible compensatory expression of endogenous heat shock genes. For these investigations, human hsp 27 was transfected into CHO cells
Publikováno v:
Journal of Thermal Biology. 19:373-383
1. 1. CHO and L929 cells were used as a model system for investigating the activities of transcriptional factors involved in hsp70 synthesis. We observed that the heat shock response for hsp70 synthesis is different in CHO and L929 cells. Hsp70 and i
Autor:
Sang H. Kim, Peter M. Corry, Charles A. Vidair, Jae H. Kim, Yong J. Lee, Elwood P. Armour, Samuel Ryu
Publikováno v:
Journal of Thermal Biology. 19:305-313
1. 1.|We investigated the relationship between heat-induced perturbation of cell cycle progression and cytotoxicity at low temperature hyperthermia in three human cell lines human breast carcinoma cells (MCF-7) and human prostatic adenocarcinoma cell
Autor:
Joong M. Cho, Zi-Zheng Hou, Sang H. Kim, Geza Erdos, Samuel Ryu, Yong J. Lee, Peter M. Corry, Jae H. Kim
Publikováno v:
Journal of Thermal Biology. 19:151-161
1. 1.|While human breast carcinoma (MCF-7) cells were resistant to heat shock, human prostatic carcinoma (DUT-145 and PC-3) cells were relatively sensitive to mild hyperthermia. For example, survival of both prostatic carcinoma cells or that of breas
Publikováno v:
Journal of Thermal Biology. 18:229-236
1. 1.An electroporation system employing an oscillating electric pulse and centrifugal force was used to introduce HSP70 or anti-HSP70 antibody into Chinese hamster ovary cells. 2. 2.There was a 1.5- or 1.9-fold increase in the amount of intracellula
Publikováno v:
Journal of Thermal Biology. 18:269-274
1. 1.A synergistic increase in the cytotoxic effects of recombinant human tumor necrosis factor-α (rhTNF-α) alone, recombinant human interferon-γ (rhIFN-γ) alone, or a combination of both drugs was observed when HT-29 and MCF-7 cells were heated
Publikováno v:
Journal of Thermal Biology. 18:165-175
1. 1.|The biochemical role of the 70 kDa constitutive heat shock protein (cHSP70) in heat-induced protein aggregation was studied by a turbidimetric assay system. 2. 2.|When rhodanese (2.5 mg/ml) was diluted 100-fold into heated cytoplasmic proteins
Autor:
Dooha Kim, Yong J. Lee
Publikováno v:
Journal of Thermal Biology. 18:41-48
1. 1.|In an effort to elucidate the mechanism by which glycerol protects cells against heat killing, the effects of glycerol on heat-induced protein aggregation were studied by employing a cell free system containing cytosolic proteins from CHO cells
Publikováno v:
Journal of Thermal Biology. 17:305-312
1. 1.|The temperature-sensitive mutant CHO-tsH1 and wild type (CHO-SC) cells became thermal resistant when cells were treated for either 2 h at 39.5°C before heating at 43°C or 2 h with 10 μg/ml cycloheximide (CHM) before and during heating at 43
Publikováno v:
Journal of Thermal Biology. 17:313-316
1. 1.|We investigated the mechanism of cycloheximide-induced heat protection. We proposed a hypothesis to account for the mechanism [Lee and Dewey (1986) Radiat. Res.106, 98–110]. 2. 2.|Cycloheximide protects cells from hyperthermic killing by mean