Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cristina Dehelean"'
Autor:
Ionut Ledeti, Renata Varut, Cristina Trandafirescu, Titus Vlase, Lenuta-Maria Suta, Cristina Dehelean, Adriana Ledeti, Gabriela Vlase, Laura Sbarcea, Denisa Circioban
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 142:1951-1961
A series of five guest–host inclusion complexes containing the antimalarial and anticancer agent artesunate (ATS) were obtained and characterized in the present study. Different cyclodextrins (CDNs) were used as hosts [α-cyclodextrin (CDN1), β-cy
Autor:
Cristina Dehelean, Denisa Circioban, Adriana Ledeti, Gabriela Vlase, Titus Vlase, Ionut Ledeti
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 142:2131-2139
Dihydroartemisinin (DHA), the hydrogenated derivative of the naturally originated sesquiterpene lactone artemisinin, is a well-known antimalarial agent that is currently researched because of its potential as an anticancer medication. Because DHA has
Autor:
Denisa Circioban, Cristina Dehelean, Adriana Ledeţi, Gabriela Vlase, Ionuţ Ledeţi, Renata Văruț, Titus Vlase, Ioana Zinuca Pavel
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 141:1041-1051
The use of cyclodextrins as carrier molecules is currently highly researched since they can improve not only the apparent water solubility and bioavailability of lipophilic drugs, but can also enhance stability or mask unpleasant tastes and smells. A
Autor:
Ionuţ Ledeţi, Dorina Coricovac, Roxana Racoviceanu, Cristina Trandafirescu, Zoltán Aigner, Codruţa Şoica, Adriana Ledeţi, Cristina Dehelean, Gabriela Vlase, Florin Borcan
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 138:3039-3054
The aim of this study was to characterize the interaction between the binary systems of albendazole (ABZ)—cyclodextrins (CDs) with pharmaceutical excipients. Hydroxyl-propyl-beta-cyclodextrin (HPBCD) and random methyl-beta-cyclodextrin (RAMEB) were
Autor:
Denisa Circioban, Titus Vlase, Ionut Ledeti, Adriana Ledeti, Cristina Dehelean, Alina Moaca, Claudia Farcas, Gabriela Vlase
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 134:741-748
In this paper, the bioactive compound artemisinin (ART) was evaluated by instrumental techniques, regarding its thermal stability and mechanism of decomposition, but for the biological activity as well, using in vitro techniques, namely the cytotoxic
Autor:
Dorina Coricovac, Denisa Circioban, Ionut Ledeti, Alina Moaca, Cristina Dehelean, Adriana Ledeti, Claudia Farcas, Gabriela Vlase, Titus Vlase
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 134:1375-1384
Artemisinin is one of the most important naturally occurring compound found in Artemisia annua, being highly active against Plasmodium falciparum, the malaria causing parasite, and currently studied in the oncological field. The aim of this study was
Autor:
Titus Vlase, Denisa Circioban, Carmen Axente, Cristina Dehelean, Ionuţ Ledeţi, Gabriela Vlase, Adriana Ledeţi
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 134:749-756
This paper presents the results obtained after the investigation of two artemisinin derived sesquiterpenes, namely artesunate and artemether, currently studied for their antitumor properties. The chosen methods of analysis included UATR–FTIR spectr
Autor:
Lenuţa-Maria Şuta, Ionuţ Ledeţi, Marius Murariu, Titus Vlase, Angelica Caunii, Adriana Ledeţi, Cristina Dehelean, Mihaela Budiul, Denisa Circioban, Gabriela Vlase, S Bolintineanu, Petru Matusz
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 131:191-199
Nortriptyline (NRT), usually conditioned as hydrochloride, is a second-generation tricyclic antidepressant that is primarily used as a treatment option for major depression and chronic pain. In this study, a compatibility evaluation between an active
Autor:
Gabriela Vlase, Angelica Caunii, Marius Murariu, Cristina Dehelean, Titus Vlase, Adriana Ledeti, Lenuta-Maria Suta, S Bolintineanu, Ionut Ledeti, Denisa Circioban
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 130:425-431
Donepezil (Don) is one of the main compounds used in the therapy of Alzheimer’s disease. In this study, donepezil hydrochloride was investigated for solid-state compatibility with several pharmaceutical excipients like calcium lactate (CaL), mannit
Autor:
Titus Vlase, Lenuta-Maria Suta, Adriana Ledeti, Gabriela Vlase, Denisa Circioban, Cristina Dehelean, Ionut Ledeti
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 131:167-173
This paper presents the results obtained in a screening study for binary adduct formation of desipramine with three dicarboxylic acids—namely succinic, malonic and glutaric acids. Adduct formation is important because most tricyclic antidepressants