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Autor:
Xiaozeng Wang, Ying Han, Wei Gao, Jia Feng, Zhuan Liao, Xiaoyan Wang, Peng Qu, Yi-Tong Ma, Miaohan Qiu, Gregg W. Stone, Shuren Ma, Jun-xia Li, Kan Yang, Jie Deng, Leisheng Ru, Zhao-Shen Li, Youlin Yang, Jiangqiu Sheng, Jinhai Wang, Shaobin Jia, Yue Li, Yi Li, Yaling Han, Sicong Ma, Ling Tao, Shaoqi Yang, Wenjuan Zhang, Min Cui, Dan Bao, Chunmeng Jiang, Yonghui Huang, Bangmao Wang, Xianxian Zhao
Publikováno v:
Journal of the American College of Cardiology. 79:116-128
Gastrointestinal bleeding is the most frequent major complication of antiplatelet therapy. In patients at low bleeding risk, however, clinically overt gastrointestinal bleeding is relatively uncommon.The authors sought to assess the effects of differ
Autor:
Dalibor Herman, Prague Trial Investigators, Petr Neuzil, Petr Kala, Klára Benešová, Jan Chovančík, Josef Stasek, Tomas Kovarnik, Pavel Hala, Martin Poloczek, Stepan Havranek, Veronika Lekesova, David Zemánek, Petr Widimsky, Petr Tousek, Jiri Holy, Pavel Osmancik, Marian Branny, Milos Taborsky, Petr Peichl, Martina Novackova, Pavel Červinka, Jiri Jarkovsky, Vlastimil Vančura, Vivek Y. Reddy, Ludek Haman
Publikováno v:
Journal of the American College of Cardiology. 79:1-14
Background The PRAGUE-17 trial demonstrated that left atrial appendage closure (LAAC) was non-inferior to non-warfarin oral anticoagulants (NOAC) for preventing major neurological, cardiovascular or bleeding events in high-risk patients with atrial f
Autor:
Kausik K. Ray, Julia Brandts
Publikováno v:
Journal of the American College of Cardiology. 78:1831-1843
Detecting familial hypercholesterolemia (FH) early and “normalizing” low-density lipoprotein (LDL) cholesterol values are the 2 pillars for effective cardiovascular disease prevention in FH. Combining lipid-lowering therapies targeting synergisti
Autor:
Marc P. Bonaca, Eric A. Secemsky, Mark R. Nehler, Rupert Bauersachs, Robert W. Yeh, Warren H. Capell, Manesh R. Patel, Sonia S. Anand, Eva Muehlhofer, Lloyd Haskell, Nicholas Govsyeyev, Connie N. Hess, Taylor Brackin, William R. Hiatt, E. Sebastian Debus, Joshua A. Beckman, Fabrizio Fanelli, Laura Mauri, Scott D. Berkowitz
Publikováno v:
Journal of the American College of Cardiology. 78:1768-1778
Background Paclitaxel drug-coated devices (DCDs) were developed to improve lower extremity revascularization (LER) patency in peripheral artery disease (PAD) but have been associated with long-term mortality. Objectives This study assessed DCD safety
Autor:
Erik Lipsic, B. Daan Westenbrink, Marie Sophie L.Y. de Koning, Pim van der Harst, Solmaz Assa, Dirk J. van Veldhuisen, Erwin Garcia, Robin P. F. Dullaart, Margery A. Connelly
Publikováno v:
Journal of the American College of Cardiology, 78(14), 1421-1432. ELSEVIER SCIENCE INC
Background: Circulating ketone bodies (KBs) are increased in patients with heart failure (HF), corresponding with increased cardiac KB metabolism and HF severity. However, the role of circulating KBs in ischemia/reperfusion remains unknown. Objective
Publikováno v:
Journal of the American College of Cardiology. 78:1671-1678
Background SBP and DBP have important associations with cardiovascular events, but are seldom considered simultaneously. Objectives This study sought to simultaneously analyze systolic blood pressure (SBP) and diastolic blood pressure (DBP) measureme
Autor:
Subhash Banerjee, E. Magnus Ohman, Sunil V. Rao, Alexander E. Sullivan, Michael G. Nanna, W. Schuyler Jones, Dominick J. Angiolillo, Jeffrey B. Washam, Deepak L. Bhatt, Jennifer A. Rymer, Sarah Cantrell, Roxana Mehran, Tracy Y. Wang
Publikováno v:
Journal of the American College of Cardiology. 78:1550-1563
Patients undergoing early surgery after coronary stent implantation are at increased risk for mortality from ischemic and hemorrhagic complications. The optimal antiplatelet strategy in patients who cannot discontinue dual antiplatelet therapy (DAPT)
Autor:
Marc S. Sabatine, Robert P. Giugliano, Jeong-Gun Park, Christopher P. Cannon, Michael A. Blazing, Andrew M. Tershakovec, Eugene Braunwald, Kazuma Oyama
Publikováno v:
Journal of the American College of Cardiology. 78:1499-1507
Background The 2018 U.S. cholesterol management guideline recommends additional lipid-lowering therapy with ezetimibe for secondary prevention in very high-risk patients with low-density l...
Autor:
Simon Bond, Joseph Cheriyan, Jean-Sébastien Silvestre, Brian Y.H. Lam, Yanyi Sun, James H.F. Rudd, Yuning Lu, Marcella Ma, Ziad Mallat, Meritxell Nus, James Harrison, Rouchelle Sriranjan, Andrew S. Sage, Xian Yu, Stephen A. Newland, Tian X. Zhao, Xiang Cheng
Publikováno v:
Journal of the American College of Cardiology. 78:1127-1142
BACKGROUND: Innate lymphoid cells type 2 (ILC2s) play critical homeostatic functions in peripheral tissues. ILC2s reside in perivascular niches and limit atherosclerosis development. OBJECTIVES: ILC2s also reside in the pericardium but their role in
Autor:
Lorena Rodríguez-González, Cristina Serrano del Castillo, Javier Flandes, Iker Fernández, María López-Álvarez, Juan Martínez-Milla, Ana-Maria Ioan, Valentin Fuster, Borja Ibanez, Carlos Galán-Arriola, Sandra Gómez-Talavera, Arnoldo Santos, César Pérez-Calvo, Agustín Clemente-Moragón, Eduardo Oliver
Publikováno v:
Journal of the American College of Cardiology
Background Severe coronavirus disease-2019 (COVID-19) can progress to an acute respiratory distress syndrome (ARDS), which involves alveolar infiltration by activated neutrophils. The beta-blocker metoprolol has been shown to ameliorate exacerbated i