Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gerwald Jogl"'
Autor:
Victor S. Batista, Jocelyn C. Newton, Gerwald Jogl, Kyle W. East, Uriel N. Morzan, George P. Lisi, Erin Skeens, Atanu Acharya, Yogesh B. Narkhede, Giulia Palermo
Publikováno v:
J Am Chem Soc
CRISPR-Cas9 is a widely employed genome-editing tool with functionality reliant on the ability of the Cas9 endonuclease to introduce site-specific breaks in double-stranded DNA. In this system, an intriguing allosteric communication has been suggeste
Publikováno v:
Journal of the American Chemical Society. 138:12678-12689
The final step in the biosynthesis of the sesquiterpenoid antibiotic pentalenolactone (1) is the highly unusual cytochrome P450-catalyzed, oxidative rearrangement of pentalenolactone F (2), involving the transient generation and rearrangement of a ne
Autor:
Brigitta Beatrix, Gerd Broeker, Christoph Kratky, Harald Bothe, ‖ and Wolfram Meyer-Klaucke, Frederic Champloy, Riikka Reitzer, Wolfgang Buckel, Gerwald Jogl, Alain Michalowicz
Publikováno v:
Journal of the American Chemical Society. 121:11780-11789
A key step in the catalytic cycle of coenzyme B12-dependent enzymes is the homolysis of the cofactor's organometallic bond, leading to the formation of a 5‘-deoxyadenosyl radical. For the adenosylcobalamin-dependent enzyme methylmalonyl CoA mutase