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Autor:
McNaughton RL; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, USA., Roemelt M, Chin JM, Schrock RR, Neese F, Hoffman BM
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2010 Jun 30; Vol. 132 (25), pp. 8645-56.
Autor:
Robert G. Griffin, Sylwia Kacprzak, Brian Hoffman, Erin Artin, JoAnne Stubbe, Hendrik Zipse, Debora Marcela Martino, Nicholas Lees, Martin Kaupp, Gregory J. S. Lohman, Marina Bennati, Stanislaw F. Wnuk
Publikováno v:
Journal of the American Chemical Society
The Escherichia coli ribonucleotide reductase (RNR) catalyzes the conversion of nucleoside diphosphates to deoxynucleotides and requires a diferric-tyrosyl radical cofactor for catalysis. RNR is composed of a 1:1 complex of two homodimeric subunits: