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Autor:
Yokoyama K; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307, USA., Uhlin U, Stubbe J
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2010 Jun 23; Vol. 132 (24), pp. 8385-97.
Autor:
Olshansky L; Department of Chemistry and Chemical Biology, Harvard University , 12 Oxford Street, Cambridge, Massachusetts 02138, United States., Pizano AA, Wei Y, Stubbe J, Nocera DG
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2014 Nov 19; Vol. 136 (46), pp. 16210-6. Date of Electronic Publication: 2014 Nov 10.
Publikováno v:
Journal of the American Chemical Society
Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms. Active E. coli class Ia RNR is an α2β2 complex that undergoes reversible, long-range proton-coupled electron transfer (PCET) over a pathwa
Publikováno v:
Journal of the American Chemical Society. 132(24)
E. coli ribonucleotide reductase catalyzes the reduction of nucleoside 5'-diphosphates into 2'-deoxynucleotides and is composed of two subunits: alpha2 and beta2. During turnover, a stable tyrosyl radical (Y*) at Y(122)-beta2 reversibly oxidizes C(43