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of 8
pro vyhledávání: '"35"'
Publikováno v:
Journal of the American Chemical Society. 133(25)
In this study, mono- and pentacyclic C(35) terpenes from Bacillus subtilis were biosynthesized via the cyclization of C(35) isoprenoid using purified enzymes, including the first identified new terpene cyclase that shows no sequence homology to any o
Autor:
Dominique Florentin, Michel Azoulay, Jean-Claude Tabet, Georges Guillerm, François Frappier, Andrée Marquet
Publikováno v:
Journal of the American Chemical Society. 115:2139-2145
Previous results led to the conclusion that the last step of biotin biosynthesis, the sulfuur insertion into dethiobiotin should involve a thiol as intermediate. The three possible thiols have been synthesized and their biological activity was evalua
Autor:
Gang Li, Christopher Tsu, Lawrence Dick, Christopher Blackburn, Paul Hales, Matthew Bogyo, Hao Li
Publikováno v:
Journal of the American Chemical Society
We have identified short N,C-capped peptides that selectively inhibit the proteasome of the malaria-causing pathogen Plasmodium falciparum. These compounds are highly potent in culture with no toxicity in host cells. One cyclic biphenyl ether compoun
Publikováno v:
Journal of the American Chemical Society. 138(22)
Circular bacteriocins, ranging from 35 to 70 amino acids, are the largest cyclic peptides produced by lactic acid bacteria to suppress growth of other bacteria. Their end-to-end cyclized backbone that enhances molecular stability is an advantage to s
Autor:
Torbjörn Norin, David S. Hermann, Lachezar Komitov, Christian Orrenius, Anders Hult, Ulf W. Gedde, Mikael Trollsas, F. Sahlén, and Sven T. Lagerwall, Jan Lindström, Per Rudquist
Publikováno v:
Journal of the American Chemical Society. 118:8542-8548
A novel cross-linked pyroelectric polymer with pronounced second-order nonlinear optical properties has been prepared. A multistep synthesis with several selective transformations including a kinetic resolution (transesterification) with the highly e
Autor:
Ana Pamplona, David L. Tierney, José J. G. Moura, Carlos D. Brondino, Marta S. P. Carepo, Joshua Telser, Brian M. Hoffman, Tran Chin Yang, Isabel Moura
Publikováno v:
Journal of the American Chemical Society. 124(2)
Crystallographic studies of the hydrogenases (Hases) from Desulfovibrio gigas (Dg) and Desulfovibrio vulgaris Miyazaki (DvM) have revealed heterodinuclear nickel-iron active centers in both enzymes. The structures, which represent the as-isolated (un
Publikováno v:
Journal of the American Chemical Society. 123(11)
Streptomyces coelicolor CH999/pJRJ2 harbors a plasmid encoding DEBS(KS1 degrees ), a mutant form of 6-deoxyerythronolide B synthase that is blocked in the formation of 6-deoxyerythronolide B (1, 6-dEB) due to a mutation in the active site of the keto
Autor:
W. B. Reynolds, Gerard Kraus
Publikováno v:
Journal of the American Chemical Society. 72:5621-5626
The extent of additive and substitutive chlorination was determined for emulsion polyisoprene, Hevea and gutta-percha chlorinated to different chlorine contents in darkness and in a nitrogen atmosphere. The maximum amount of additive chlorine that ca