Zobrazeno 1 - 10
of 26
pro vyhledávání: '"35"'
Autor:
Tim P Hogervorst, Jeroen D. C. Codée, Xianwen Lou, E. W. Meijer, Gijsbert A. van der Marel, René P. M. Lafleur, Simone I. S. Hendrikse, Lu Su
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 141(35), 13877-13886
Journal of the American Chemical Society, 141(35), 13877-13886. American Chemical Society
Journal of the American Chemical Society, 141(35), 13877-13886
Journal of the American Chemical Society, 141(35), 13877-13886. American Chemical Society
Polysaccharides present in the glycocalyx and extracellular matrix are highly important for a multitude of functions. Oligo- and polysaccharides-based biomaterials are being developed to mimic the glycocalyx, but the spatial functionalization of thes
Publikováno v:
Journal of the American Chemical Society. 140:15744-15752
Class Ia ribonucleotide reductase (RNR) of Escherichia coli contains an unusually stable tyrosyl radical cofactor in the β2 subunit (Y122•) necessary for nucleotide reductase activity. Upon binding the cognate α2 subunit, loaded with nucleoside d
Autor:
Christian Hoppmann, Caiyun Fu, Roshanak Irannejad, Tomonori Kobayashi, Bing Yang, Lei Wang, Nanxi Wang
Publikováno v:
Journal of the American Chemical Society, vol 140, iss 35
Acidic vesicles and organelles play fundamental roles in a broad range of cellular events such as endocytosis, lysosomal degradation, synaptic transmission, pathogen fate, and drug delivery. Fluorescent reporters will be invaluable for studying these
Publikováno v:
Journal of the American Chemical Society. 139:16657-16665
Ribonucleotide reductases (RNR) catalyze the reduction of nucleotides to deoxynucleotides through a mechanism involving an essential cysteine based thiyl radical. In the E. coli class 1a RNR the thiyl radical (C439•) is a transient species generate
Autor:
Brandon Q. Mercado, Scott J. Miller, Nadia C. Abascal, Eric K. Paulson, Anthony J. Metrano, Anna E. Hurtley
Publikováno v:
Journal of the American Chemical Society
X-ray crystallography has been applied to the structural analysis of a series of tetrapeptides that were previously assessed for catalytic activity in an atroposelective bromination reaction. Common to the series is a central Pro-Xaa sequence, where
Publikováno v:
Journal of the American Chemical Society, vol 137, iss 35
Optical modulation of proteins provides superior spatiotemporal resolution for understanding biological processes, and photoswitches built on light-sensitive proteins have been significantly advancing neuronal and cellular studies. Small molecule pho
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2014, 136 (35), pp.12283-12295. ⟨10.1021/ja504063c⟩
Journal of the American Chemical Society, American Chemical Society, 2014, 136 (35), pp.12283-12295. ⟨10.1021/ja504063c⟩
International audience; Metabolic chemical reporters (MCRs) of glycosylation are analogues of monosaccharides that contain bioorthogonal functionalities and enable the direct visualization and identification of glycoproteins from living cells. Each M
Autor:
Jeremy M. Smith, Brian M. Hoffman, Martin L. Kirk, Benjamin W. Stein, Deepak Subedi, George E. Cutsail
Publikováno v:
Journal of the American Chemical Society
The recently synthesized and isolated low-coordinate Fe(V) nitride complex has numerous implications as a model for high-oxidation states in biological and industrial systems. The trigonal [PhB((t)BuIm)3Fe(V)≡N](+) (where (PhB((t)BuIm)3(-) = phenyl
Publikováno v:
Journal of the American Chemical Society. 139(11)
The C-terminal selective electrophilic activation of polypeptides is essential for site-specific peptide modification and conjugation techniques such as Native Chemical Ligation (NCL). Peptide C-terminal α-thioesters are particularly valuable precur
Autor:
Alexey Silakov, Denise A. Conner, Wei Jiang, Mohammad R. Seyedsayamdost, Bigna Wörsdörfer, Kenichi Yokoyama, J. Martin Bollinger, JoAnne Stubbe, Carsten Krebs, Jovan Livada
Publikováno v:
Journal of the American Chemical Society. 135:8585-8593
The class Ia ribonucleotide reductase (RNR) from Escherichia coli (Ec) employs a free-radical mechanism, which involves bidirectional translocation of a radical equivalent or “hole” over a distance of ∼35 Å from the stable diferric/tyrosyl-rad