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Autor:
Alexander L. Satz, Thomas C. Bruice
Publikováno v:
Journal of the American Chemical Society. 123:2469-2477
A tripyrrole peptide-Hoechst conjugate (FPH-1) has been designed which recognizes nine dA/dT base pair A/T rich dsDNA sequences at subnanomolar concentrations and complexes its targets at near diffusion controlled rates to form a fluorescent product.
Autor:
Jerzy Leszczynski, Jan Florián
Publikováno v:
Journal of the American Chemical Society. 118:3010-3017
The energetic provisions for Lowdin's DNA mutational mechanism (Lowdin, P. O. Rev. Mod. Phys. 1963, 35, 724) of the formation of substitution DNA mutations were investigated for the guanine·cytosine Watson−Crick base pair. The structures studied i
Publikováno v:
Journal of the American Chemical Society. 130(43)
A solution state NMR study has shown that d(G4T3G4) in the presence of (15)NH4(+) ions folds into a single bimolecular G-quadruplex structure in which its G-tracts are antiparallel and the two T3 loops span along the edges of the outer G-quartets on