Zobrazeno 1 - 10
of 32
pro vyhledávání: '"35"'
Autor:
R. Adam Kinney, Bo Zhang, Rebecca L. McNaughton, Russ Hille, Muralidharan Shanmugam, Brian M. Hoffman
Publikováno v:
Journal of the American Chemical Society. 132:14015-14017
The formaldehyde-inhibited Mo(V) state of xanthine oxidase (I) has been studied for four decades, yet it has not proven possible to distinguish unequivocally among the several structures proposed for this form. The uniquely large isotropic hyperfine
Autor:
Clive Yik-Sham Chung, Pei Liu, Kevin J. Bruemmer, Evan W. Miller, Christopher J. Chang, Kaoru Saijo, Yuki Nishikawa, Sumin Lee, Itaru Hamachi, Laura Craciun
Publikováno v:
Journal of the American Chemical Society, vol 142, iss 35
J Am Chem Soc
J Am Chem Soc
Copper is a required nutrient for life and particularly important to the brain and central nervous system. Indeed, copper redox activity is essential to maintaining normal physiological responses spanning neural signaling to metabolism, but at the sa
Autor:
Bryan E. G. Lucier, Xiaoling Wang, Shijia Jiang, Kuizhi Chen, Christel Gervais, Zhehong Gan, Ivan Hung, Christian Bonhomme, Yining Huang, Vinicius Abilio Martins, Jun Xu, Anmin Zheng
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, 142 (35), pp.14877-14889. ⟨10.1021/jacs.0c02810⟩
J Am Chem Soc
Journal of the American Chemical Society, American Chemical Society, 2020, 142 (35), pp.14877-14889. ⟨10.1021/jacs.0c02810⟩
J Am Chem Soc
International audience; The spectroscopic study of oxygen, a vital element in materials, physical, and life sciences, is of tremendous fundamental and practical importance. 17O solid-state NMR (SSNMR) spectroscopy has evolved into an ideal site-speci
Publikováno v:
J Am Chem Soc
We report an air-stable diradical dication of chiral D(2)-symmetric conjoined bis[5]diazahelicene with unprecedented high spin (triplet) ground state, singlet triplet energy gap, ΔE(ST) = 0.3 kcal mol(−1). The diradical dication possesses closed-s
Autor:
Petra Hänzelmann, Sowmya Subramanian, Michael K. Johnson, Brian M. Hoffman, Heather L. Hernandez, Hermann Schindelin, Nicholas S. Lees
Publikováno v:
Journal of the American Chemical Society. 131:9184-9185
The S-adenosylmethionine-dependent enzyme MoaA, in concert with MoaC, catalyzes the first step of molybdenum cofactor biosynthesis, the conversion of guanosine 5'-triphosphate (5'-GTP) into precursor Z. A published X-ray crystal structure of MoaA wit
Publikováno v:
Journal of the American Chemical Society. 141:10821-10829
High fidelity human mitochondrial DNA polymerase (Pol γ) contains two active sites, a DNA polymerization site (pol) and a 3′−5′ exonuclease site (exo) for proofreading. Although separated by 35 Å, coordination between the pol and exo sites is
Publikováno v:
Journal of the American Chemical Society. 140:15744-15752
Class Ia ribonucleotide reductase (RNR) of Escherichia coli contains an unusually stable tyrosyl radical cofactor in the β2 subunit (Y122•) necessary for nucleotide reductase activity. Upon binding the cognate α2 subunit, loaded with nucleoside d
Autor:
Christian Hoppmann, Caiyun Fu, Roshanak Irannejad, Tomonori Kobayashi, Bing Yang, Lei Wang, Nanxi Wang
Publikováno v:
Journal of the American Chemical Society, vol 140, iss 35
Acidic vesicles and organelles play fundamental roles in a broad range of cellular events such as endocytosis, lysosomal degradation, synaptic transmission, pathogen fate, and drug delivery. Fluorescent reporters will be invaluable for studying these
Publikováno v:
Journal of the American Chemical Society. 139:16657-16665
Ribonucleotide reductases (RNR) catalyze the reduction of nucleotides to deoxynucleotides through a mechanism involving an essential cysteine based thiyl radical. In the E. coli class 1a RNR the thiyl radical (C439•) is a transient species generate
Autor:
Di Kang, Kevin W. Plaxco, Demosthenes P. Morales, Sheng Sun, Frederick W. Dahlquist, Martin Kurnik
Publikováno v:
Journal of the American Chemical Society, vol 139, iss 35
Here we demonstrate a new class of reagentless, single-step sensors for monitoring protein-protein and protein-peptide interactions that is the electrochemical analog of fluorescence polarization (fluorescence anisotropy), a versatile optical approac